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Src 抗体

Src 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 17AT28 unconjugated
产品编号 ABIN387822
发货至: 中国
  • 抗原 See all Src 抗体
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    适用
    • 230
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    • 121
    • 9
    • 8
    • 8
    • 6
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    • 1
    • 1
    人, 小鼠
    宿主
    • 244
    • 18
    • 1
    小鼠
    克隆类型
    • 222
    • 41
    单克隆
    标记
    • 123
    • 22
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    • 6
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    • 4
    • 1
    This Src antibody is un-conjugated
    应用范围
    • 197
    • 139
    • 68
    • 55
    • 53
    • 35
    • 30
    • 29
    • 23
    • 12
    • 9
    • 7
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    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This Src antibody is generated from mouse immunized with a recombinant protein of full length human SRC.
    克隆位点
    17AT28
    亚型
    IgG1
    Top Product
    Discover our top product Src Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:500. WB: 1:2000. WB: 1:100~500. WB: 1:100~500. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Nicholson, Seta, Lee, Morgan: "MicroRNA-203 mimics age-related aortic smooth muscle dysfunction of cytoskeletal pathways." in: Journal of cellular and molecular medicine, Vol. 21, Issue 1, pp. 81-95, (2017) (PubMed).

    Marcotte, Smith, Sanguin-Gendreau, McDonough, Muller: "Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 8, pp. 2808-13, (2012) (PubMed).

    Chen, Li, Zhang, Yi, Chen, Wang, Zhang: "Src-stimulated IRTKS phosphorylation enhances cell migration." in: FEBS letters, Vol. 585, Issue 19, pp. 2972-8, (2011) (PubMed).

  • 抗原
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    别名
    Src (Src 产品)
    别名
    AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody
    物质类
    Viral Protein
    背景
    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
    分子量
    59835
    基因ID
    6714
    NCBI登录号
    NP_005408, NP_938033
    UniProt
    P12931
    途径
    JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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