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SOX2 抗体

SOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 57CT23-3-4 unconjugated
产品编号 ABIN387798
发货至: 中国
  • 抗原 See all SOX2 抗体
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    适用
    • 203
    • 96
    • 69
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    • 11
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    宿主
    • 165
    • 42
    • 2
    小鼠
    克隆类型
    • 163
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    单克隆
    标记
    • 103
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    This SOX2 antibody is un-conjugated
    应用范围
    • 165
    • 109
    • 47
    • 46
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    • 18
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    SOX2 recombinant protein is used to produce this monoclonal antibody.
    克隆位点
    57CT23-3-4
    亚型
    IgG1
    Top Product
    Discover our top product SOX2 Primary Antibody
  • 应用备注
    IF: 1:100. IF: 1:10~50. WB: 1:200~2000. WB: 1:200~2000. WB: 1:1000. WB: 1:4000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Chen, Ou, Song, Xian, Ouyang, Xie, Xue, Sun: "Generation of integration-free induced pluripotent stem cells (GZHMUi001-A) by reprogramming peripheral blood mononuclear cells from a 47, XXX syndrome patient." in: Stem cell research, Vol. 23, pp. 57-60, (2018) (PubMed).

    Horibe, Hirohashi, Asano, Mariya, Suzuki, Takaya, Saijo, Shionoya, Kubo, Nakatsugawa, Kanaseki, Tsukahara, Watanabe, Atsuyama, Toji, Hirano, Hasegawa, Takahashi, Sato, Torigoe: "Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy." in: PLoS ONE, Vol. 12, Issue 3, pp. e0171460, (2017) (PubMed).

    Zheng, Pang, Gu, Gao, Zhang, Pang, Liu: "Melatonin Inhibits Glioblastoma Stem-like cells through Suppression of EZH2-NOTCH1 Signaling Axis." in: International journal of biological sciences, Vol. 13, Issue 2, pp. 245-253, (2017) (PubMed).

    Tilson, Haley, Triantafillu, Dozier, Langford, Gillespie, Kim: "ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132823, (2015) (PubMed).

  • 抗原
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    别名
    SOX2 (SOX2 产品)
    背景
    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
    分子量
    34310
    基因ID
    6657
    NCBI登录号
    NP_003097
    UniProt
    P48431
    途径
    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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