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Nanog 抗体

NANOG 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 60CT77-1-1 unconjugated
产品编号 ABIN387791
发货至: 中国
  • 抗原 See all Nanog (NANOG) 抗体
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    适用
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    宿主
    • 123
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    小鼠
    克隆类型
    • 118
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    单克隆
    标记
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    This Nanog antibody is un-conjugated
    应用范围
    • 110
    • 60
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This NANOG monoclonal antibody is generated from mouse immunized with NANOG recombinant protein.
    克隆位点
    60CT77-1-1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product NANOG Primary Antibody
  • 应用备注
    WB: 1:100~250. WB: 1:100~250. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    别名
    NANOG (NANOG 产品)
    别名
    2410002E02Rik antibody, ENK antibody, ecat4 antibody, NANOG antibody, hacp antibody, wu:fd19e04 antibody, wu:fd20a07 antibody, zgc:193933 antibody, Nanog homeobox antibody, nanog homeobox antibody, Nanog antibody, NANOG antibody, nanog antibody
    背景
    Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).
    分子量
    34620
    基因ID
    79923
    NCBI登录号
    NP_079141
    UniProt
    Q9H9S0
    途径
    Stem Cell Maintenance
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