NEDD9 抗体 (Internal Region)
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- 抗原 See all NEDD9 抗体
- NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
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抗原表位
- Internal Region
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适用
- 人, 大鼠, 小鼠, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This NEDD9 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to NEDD9. This antibody is expected to recognise isoform 1 only.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence NKPQNKCDDLDR, from the internal region of the protein sequence
- Top Product
- Discover our top product NEDD9 Primary Antibody
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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 60-174) antibody
NEDD9 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 82-398) antibodyNEDD9 适用: 人, 大鼠, 小鼠 WB, IF, IP, ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 101-200) antibodyNEDD9 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (Internal Region) antibodyNEDD9 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 82-398), (AA 843) antibodyNEDD9 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 1-834) antibodyNEDD9 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 1-834) antibodyNEDD9 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) antibodyNEDD9 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 335-363) antibodyNEDD9 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 68-151) antibodyNEDD9 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0,5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
- 别名
- NEDD9 (NEDD9 产品)
- 别名
- NEDD9 antibody, CAS-L antibody, CAS2 antibody, CASL antibody, CASS2 antibody, HEF1 antibody, Cas-L antibody, CasL antibody, E230025G09Rik antibody, neural precursor cell expressed, developmentally down-regulated 9 antibody, neural precursor cell expressed, developmentally down-regulated gene 9 antibody, NEDD9 antibody, Nedd9 antibody
- 背景
- HEF1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation. The Cas family of docking proteins have been the subject of intense research because of their role in cell motility, growth, apoptosis and oncogenic transformation. These proteins are substrates of focal adhesion kinase (FAK) and the Src family of tyrosine kinases, two active targets for drug development. HEF1 protein production increases levels of mRNA transcripts that encode proteins associated with motility, cell transformation and invasiveness, including several metalloproteinases, MLCK, p160ROCK and ErbBi. HEF1 overproduction also mediates apoptosis in epithelial-derived cell lines, including MCF7 and HeLa cells. Recent clinical studies at another institution have found that overexpression of BCAR1 (p130Cas), a related protein, is associated with tamoxifen resistance. This highlights the importance of studying the role of this family of proteins in cancer prognosis.Synonyms: CASL, CASS2, Enhancer of filamentation 1, Neural precursor cell expressed developmentally down-regulated protein 9, hEF1
- 基因ID
- 4739
- NCBI登录号
- NP_001135865
- UniProt
- Q14511
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