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Desmin 抗体 (C-Term)

DES 适用: 人, 小鼠, 大鼠, 犬, Cow WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375065
发货至: 中国
  • 抗原 See all Desmin (DES) 抗体
    Desmin (DES)
    抗原表位
    • 17
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    • 7
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    C-Term
    适用
    • 149
    • 80
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    • 11
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    人, 小鼠, 大鼠, 犬, Cow
    宿主
    • 111
    • 37
    • 2
    山羊
    克隆类型
    • 106
    • 45
    多克隆
    标记
    • 76
    • 8
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    • 5
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    • 3
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    • 1
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    • 1
    This Desmin antibody is un-conjugated
    应用范围
    • 115
    • 68
    • 55
    • 44
    • 26
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    • 14
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    • 6
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    Western Blotting (WB)
    特异性
    This antibody reacts to Desmin.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-RDGEVVSEATQQQHE, from the C Terminus of the protein sequence
    Top Product
    Discover our top product DES Primary Antibody
  • 应用备注
    Peptide ELISA: 1/2000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Desmin (DES)
    别名
    Desmin (DES 产品)
    别名
    DES antibody, des-b antibody, MGC80853 antibody, des antibody, csm1 antibody, csm2 antibody, desm antibody, cmd1i antibody, MGC75911 antibody, LOC100220724 antibody, desmin antibody, cb290 antibody, fb59a12 antibody, wu:fb59a12 antibody, zgc:109859 antibody, CSM1 antibody, CSM2 antibody, LGMD2R antibody, wu:fc11d08 antibody, zgc:154009 antibody, des-a antibody, MGC52614 antibody, desmin antibody, desmin, gene 1 L homeolog antibody, desmin, gene 1 antibody, desmin a antibody, desmin b antibody, desmin, gene 1 S homeolog antibody, desmin, gene 2 S homeolog antibody, DES antibody, des.1.L antibody, des.1 antibody, des antibody, desma antibody, Des antibody, desmb antibody, des.1.S antibody, des.2.S antibody
    背景
    Desmins belongs to the intermediate filament family, and are class III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures. Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells. A desmin related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I). CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function. Antidesmin antibodies are useful in identification of tumours of myogenic origin.Synonyms: DES
    基因ID
    1674
    NCBI登录号
    NP_001918
    UniProt
    P17661
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