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BAG5 抗体 (Internal Region)

BAG5 适用: 人, 小鼠, 大鼠 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375061
发货至: 中国
  • 抗原 See all BAG5 抗体
    BAG5 (BCL2-Associated Athanogene 5 (BAG5))
    抗原表位
    • 15
    • 12
    • 11
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 55
    • 26
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 68
    • 4
    • 1
    山羊
    克隆类型
    • 71
    • 2
    多克隆
    标记
    • 37
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAG5 antibody is un-conjugated
    应用范围
    • 47
    • 28
    • 13
    • 13
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to BAG5. This antibody is expected to recognise reported isoform a and isoform b.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence DPQGEEKCKAARKQ, from the internal region of the protein sequence
    Top Product
    Discover our top product BAG5 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    BAG5 (BCL2-Associated Athanogene 5 (BAG5))
    别名
    BAG5 (BAG5 产品)
    别名
    BAG-5 antibody, bag-5 antibody, 1600025G07Rik antibody, 4930405J06Rik antibody, zgc:114117 antibody, BAG5 antibody, ATBAG5 antibody, BCL-2-associated athanogene 5 antibody, F12F1.7 antibody, F12F1_7 antibody, BCL2 associated athanogene 5 antibody, BCL2-associated athanogene 5 antibody, BCL-2-associated athanogene 5 antibody, BAG5 antibody, bag5 antibody, Bag5 antibody
    背景
    BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. A BAG domain near the C terminus, may bind and inhibit the chaperone activity of Hsc70/Hsp70. It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti apoptotic function. It is believed that BAG5 will play an important role in the mechanisms of neuronal death. BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.Synonyms: BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, KIAA0873
    基因ID
    9529, 9606
    UniProt
    Q9UL15
    途径
    SARS-CoV-2 Protein Interactome
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