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CACNA2D1 抗体 (Internal Region)

CACNA2D1 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374788
发货至: 中国
  • 抗原 See all CACNA2D1 抗体
    CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
    抗原表位
    • 12
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 43
    • 16
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 44
    • 1
    山羊
    克隆类型
    • 45
    多克隆
    标记
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNA2D1 antibody is un-conjugated
    应用范围
    • 29
    • 27
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    C-QEIFNKYNKD KKVR
    特异性
    This antibody recognizes CACNA2D1.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Synthetic peptide from the internal region of Human CACNA2D1 (NP_000713.2) Genename: CACNA2D1
    Top Product
    Discover our top product CACNA2D1 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western Blot: 0.03 - 0.1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
    别名
    CACNA2D1 (CACNA2D1 产品)
    别名
    CACNA2D1 antibody, DKFZp469K2211 antibody, CACNA2 antibody, CACNL2A antibody, CCHL2A antibody, Ca(v)alpha2delta1 antibody, Cacna2 antibody, Cchl2a antibody, CCHLA2 antibody, DHSCCA antibody, calcium voltage-gated channel auxiliary subunit alpha2delta 1 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 1 antibody, calcium channel, voltage-dependent, alpha2/delta subunit 1 antibody, CACNA2D1 antibody, cacna2d1 antibody, Cacna2d1 antibody
    背景
    Voltage-sensitive calcium channels mediate the entry of calcium into many types of excitable cells and thus play a key role in neurotransmitter release and excitation-contraction (E-C) coupling. The 1,4-dihydropyridines (DHPs) are synthetic organic compounds which can be used to identify the L-type calcium channels that are found in all types of vertebrate muscle, neuronal and neuroendocrine cells. The DHP receptor is part of the L-type calcium channel complex and is thought to be the voltage sensor in E-C coupling. The purified DHP receptor isolated from triads is composed of at least four subunits. The alpha-1 subunit contains the binding site for the DHPs and shows high sequence homology to the voltage gated sodium channel. The alpha-2 subunit is a large glycoprotein associated with the DHP receptor which was first described in skeletal muscle and is also found in high concentrations in other excitable tissues such as cardiac muscle and brain and in low concentrations in most other tissues studied. The other two subunits that co-purify with the DHP receptor are termed beta and gamma.Synonyms: CACNL2A, CCHL2A, MHS3, Voltage-dependent calcium channel subunit alpha-2/delta-1
    分子量
    123 kDa (NP_000713.2)
    基因ID
    781, 9606
    UniProt
    P54289
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