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UNC13D 抗体 (Internal Region)

UNC13D 适用: 人, 小鼠, 大鼠, 犬 WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374716
发货至: 中国
  • 抗原 See all UNC13D 抗体
    UNC13D (Unc-13 Homolog D (UNC13D))
    抗原表位
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 25
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 21
    • 3
    • 2
    山羊
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 22
    • 2
    • 1
    • 1
    This UNC13D antibody is un-conjugated
    应用范围
    • 21
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts to Munc13-4 / UNC13D.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-ETQKHKKDLHPLFD, from the internal region of the protein sequence
    Top Product
    Discover our top product UNC13D Primary Antibody
  • 应用备注
    ELISA: 1/128000. Western Blot: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: 2.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    UNC13D (Unc-13 Homolog D (UNC13D))
    别名
    UNC13D (UNC13D 产品)
    别名
    FHL3 antibody, HLH3 antibody, HPLH3 antibody, Munc13-4 antibody, UNC13D antibody, 2610108D09Rik antibody, Jinx antibody, mFLJ00067 antibody, Unc13h4 antibody, BIGH3 antibody, CDB1 antibody, CDG2 antibody, CDGG1 antibody, CSD antibody, CSD1 antibody, CSD2 antibody, CSD3 antibody, EBMD antibody, LCD1 antibody, unc-13 homolog D antibody, unc-13 homolog D (C. elegans) antibody, transforming growth factor beta induced antibody, UNC13D antibody, Unc13d antibody, TGFBI antibody, unc13d antibody, un13d antibody
    背景
    Secretion of the contents of cytolytic granules at the immunologic synapse is a highly regulated process essential for lymphocyte cytotoxicity. This process requires the rapid transfer of perforin containing lytic granules to the target cell interface, followed by their docking and fusion with the plasma membrane. Munc 13-4 localises with cytotoxic granules at the immunologic synapse. Munc 13-4 is essential for the priming step of cytolytic granule secretion preceding vesicle membrane fusion. There are two named isoforms.Synonyms: Munc13-4, Protein unc-13 homolog D
    基因ID
    201294, 9606
    UniProt
    Q70J99
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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