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AGO1 抗体 (Internal Region)

EIF2C1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374655
发货至: 中国
  • 抗原 See all AGO1 (EIF2C1) 抗体
    AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
    抗原表位
    • 10
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 32
    • 17
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 35
    • 1
    • 1
    • 1
    山羊
    克隆类型
    • 34
    • 4
    多克隆
    标记
    • 25
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AGO1 antibody is un-conjugated
    应用范围
    • 25
    • 13
    • 9
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody recognizes Protein eIF2C1 /AGO1. This product is not expected to cross-react with EIF2C2, EIF2C3 and EIF2C4.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat and Canine (Dog).
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence C-KNASYNLDPYIQEF, from the internal region of the protein sequence according to NP_036331.1.
    Top Product
    Discover our top product EIF2C1 Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit: 1/16000. Western Blot: 0.3-1 μg/mL. In transfected HEK293 transiently expressing Human EIF2C1bands of approx.110 kDa and 30 kDa are observed. The 110 kDa band is not observed in thenon-transfected HEK293.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
    别名
    EIF2C1 / AGO1 (EIF2C1 产品)
    别名
    Ago antibody, Ago-1 antibody, Ago1 antibody, CG6671 antibody, Dm Ago1 antibody, Dmel\\CG6671 antibody, MRE20 antibody, ago1 antibody, ago1-1 antibody, anon-WO0257455.29 antibody, dAGO1 antibody, dAgo1 antibody, l(2)04845 antibody, l(2)4845 antibody, l(2)k00208 antibody, l(2)k08121 antibody, GB12654 antibody, dsim_GLEANR_9718 antibody, DsimGD25729 antibody, GD25729 antibody, EIF2C1 antibody, EIF2C antibody, GERP95 antibody, Q99 antibody, Eif2c1 antibody, ARGONAUTE 1 antibody, T1N15.2 antibody, T1N15_2 antibody, Argonaute-1 antibody, protein argonaute-2 antibody, argonaute 1 antibody, Argonaute 1 antibody, protein argonaute-1 antibody, argonaute 1, RISC catalytic component antibody, argonaute RISC catalytic subunit 1 antibody, Stabilizer of iron transporter SufD / Polynucleotidyl transferase antibody, AGO1 antibody, LOC552062 antibody, ago1 antibody, LOC659936 antibody, Dsim\AGO1 antibody, Ago1 antibody, LOC100386910 antibody, LOC100482671 antibody, LOC475337 antibody
    背景
    Ago1 belongs to the argonaute family and contains 1 PAZ and 1 Piwi domain. It is required for G1 arrest and mating in response to nitrogen starvation. It is also known as cell cycle control protein through it's regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. It is required, indirectly, for regulated hyperphosphorylation of cdc2. Ago 1 also has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. It has been shown to be non-essential for siRNA-directed target RNA cleavage but is needed for the production of mature miRNA that affects miRNA-directed RNA cleavage.Synonyms: Argonaute-1, Eukaryotic translation initiation factor 2C1, RNA-binding protein Q99, eIF-2C1, hAgo-1
    分子量
    97.2kDa according to NP_036331.1
    基因ID
    26523
    NCBI登录号
    NP_036331
    UniProt
    Q9UL18
    途径
    Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Transport, Regulation of Actin Filament Polymerization, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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