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PVALB 抗体 (C-Term)

PVALB 适用: 人, 大鼠 WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374572
发货至: 中国
  • 抗原 See all PVALB 抗体
    PVALB (Parvalbumin (PVALB))
    抗原表位
    • 15
    • 7
    • 7
    • 4
    • 1
    • 1
    C-Term
    适用
    • 40
    • 36
    • 29
    • 15
    • 1
    人, 大鼠
    宿主
    • 49
    • 20
    • 2
    • 1
    山羊
    克隆类型
    • 43
    • 29
    多克隆
    标记
    • 23
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PVALB antibody is un-conjugated
    应用范围
    • 40
    • 30
    • 26
    • 16
    • 16
    • 13
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    C-GVDEFSTLVA ES
    特异性
    This antibody recognizes Parvalbumin.
    交叉反应 (详细)
    Species reactivity (tested):Human, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the C Terminus of the protein sequence according to NP_002845.1.
    Top Product
    Discover our top product PVALB Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32000. Western Blot: 0.1-0.3 μg/mL. Approx 12 kDa band observed in Human Brain lysates (calculated MW of 12.2 kDa accordingto NP_002845.1). Approx 10-12 kDa band observed in rat skeletal muscle and in rat heart cells transfectedwith human PVALB, but not in untransfected rat heart cells. (1)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PVALB (Parvalbumin (PVALB))
    别名
    Parvalbumin alpha / PVALB (PVALB 产品)
    别名
    D22S749 antibody, PV antibody, Parv antibody, Pva antibody, PALB1 antibody, pvalb1 antibody, MGC107903 antibody, parvalbumin antibody, parvalbumin, gene 1 antibody, parvalbumin, gene 1 S homeolog antibody, PVALB antibody, Pvalb antibody, pvalb.1 antibody, pvalb.1.S antibody
    背景
    Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
    基因ID
    5816
    NCBI登录号
    NP_002845
    UniProt
    P20472
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