LCP2 抗体 (N-Term)
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- 抗原 See all LCP2 抗体
- LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Pig, Cow, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This LCP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 序列
- C-ALRNVPFRSE V
- 特异性
- This antibody recognizes LCP2.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine, Pig, Cow.
Species reactivity (tested):Human. - 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- 免疫原
- Peptide from the N Terminus of the protein sequence according to NP_005556.
- Top Product
- Discover our top product LCP2 Primary Antibody
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anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 202-463) antibody
LCP2 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (N-Term) antibodyVerified LCP2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 216-434) antibodyLCP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 284-533) antibodyLCP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 94-143), (pTyr128) antibodyLCP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (pTyr128) antibodyLCP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 46-80) antibodyLCP2 适用: 人 WB 宿主: 兔 Polyclonal RB56244 unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 303-337) antibodyLCP2 适用: 人 WB 宿主: 兔 Polyclonal RB56245 unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 216-434) antibodyLCP2 适用: 人 WB, IP, FACS 宿主: 小鼠 Monoclonal H76 unconjugated
anti-Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) antibodyLCP2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/32,000. Western Blot: 0.5-2 μg/mL. Detects a band of Approx 75 kDa (Predicted Molecular Weight65 kDa). Positive Control: Jurkat lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- 抗原
- LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
- 别名
- LCP2 (LCP2 产品)
- 别名
- AI323664 antibody, BB161688 antibody, SLP-76 antibody, SLP76 antibody, twm antibody, Slp76 antibody, lymphocyte cytosolic protein 2 antibody, Lcp2 antibody, LCP2 antibody
- 背景
- LCP2 is a hematopoietic cell-specific adaptor protein that is crucial for T-cell receptor (TCR) signaling, hemostasis and platelet function. TCR ligation and fibrinogen binding to integrin alpha 2 beta 3 stimulates the phosphorylation of the tyrosine residues in the amino terminus, and facilitates SLP76 binding to the SH2 domain of Vav, which can activate JNK. SLP76 also comprises a proline-rich domain region that associates with the SH3 domain of Grb2 linking SLP76 to the Ras to Raf to ERK1 & 2 signaling pathway, LAT, PLC gamma, Fyn-binding protein (SLAP130), the SH2 containing phosphatase 1 and Nck, which mediates the regulation of cytoskeletal actin polymerization. Phosphorylation of tyrosine 145 has been shown to be important for optimal SLP76 function.Synonyms: LCP2, Lymphocyte cytosolic protein 2, SH2 domain-containing leukocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein, SLP76
- 基因ID
- 3937
- NCBI登录号
- NP_005556
- UniProt
- Q13094
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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