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FOXO3 抗体 (C-Term)

FOXO3 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374440
发货至: 中国
  • 抗原 See all FOXO3 抗体
    FOXO3 (Forkhead Box O3 (FOXO3))
    抗原表位
    • 30
    • 16
    • 13
    • 8
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    C-Term
    适用
    • 176
    • 130
    • 121
    • 9
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    • 5
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    • 5
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    • 4
    • 3
    • 2
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    • 1
    人, 小鼠, 大鼠, 犬, Cow, Pig
    宿主
    • 172
    • 5
    • 1
    • 1
    山羊
    克隆类型
    • 162
    • 17
    多克隆
    标记
    • 71
    • 15
    • 10
    • 10
    • 10
    • 10
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    • 7
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    This FOXO3 antibody is un-conjugated
    应用范围
    • 113
    • 61
    • 52
    • 35
    • 28
    • 27
    • 14
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    • 14
    • 5
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    • 1
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-GAKQASSQSW VPG
    特异性
    This antibody recognizes FKHRL1/FOXO3A.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine, Porcine, Bovine.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide from the C Terminus of the protein sequence according to according to NP_001446.1. Genename: FOXO3
    Top Product
    Discover our top product FOXO3 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32,000. Western Blot: Approx 90 kDa band observed in human Brain and Heart lysates (calculatedMW of 71.0 kDa according to NP_001446 and NP_963853). Recommended concentration: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FOXO3 (Forkhead Box O3 (FOXO3))
    别名
    FOXO3 / FKHRL1 (FOXO3 产品)
    别名
    AF6q21 antibody, FKHRL1 antibody, FKHRL1P2 antibody, FOXO2 antibody, FOXO3A antibody, zgc:92176 antibody, wu:fb50g02 antibody, wu:fi33f07 antibody, Fkhrl1 antibody, Foxo3a antibody, FoxO3A antibody, 1110048B16Rik antibody, 2010203A17Rik antibody, C76856 antibody, Fkhr2 antibody, FOXO-3 antibody, FOXO3 antibody, foxo3a antibody, xfoxo3 antibody, foxO3 antibody, foxO antibody, fkhr antibody, foxo5 antibody, wu:fj65a12 antibody, zFkhr antibody, forkhead box O3 antibody, forkhead box O3A antibody, forkhead box O3 L homeolog antibody, forkhead box O3b antibody, FOXO3 antibody, foxo3a antibody, Foxo3 antibody, foxo3.L antibody, foxo3 antibody, foxO3 antibody, foxo3b antibody
    背景
    FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two tiered mechanism of phosphorylation and acetylation. FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors. It recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. FOXO3a has been shown to induce cell growth arrest to effect tumor suppression and FOXO3A genotype is strongly associated with human longevitySynonyms: AF6q21 protein, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1
    基因ID
    2309
    NCBI登录号
    NP_001446
    UniProt
    O43524
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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