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PITPNM1 抗体 (C-Term)

PITPNM1 适用: 人, 小鼠, Cow, 犬 WB, IF 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374422
发货至: 中国
  • 抗原 See all PITPNM1 抗体
    PITPNM1 (Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1))
    抗原表位
    • 15
    • 9
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 36
    • 19
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, Cow, 犬
    宿主
    • 49
    • 1
    • 1
    山羊
    克隆类型
    • 50
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PITPNM1 antibody is un-conjugated
    应用范围
    • 24
    • 23
    • 13
    • 13
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    C-KARSISLKLD SEE
    特异性
    This antibody detects NIR2 at C-term and is expected to recognise both reported isoforms.
    交叉反应 (详细)
    Species reactivity (expected):Human, Dog, Cow.
    Species reactivity (tested):Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from the C-Terminus of the protein sequence according to NP_004901.2, NP_001124320.1. Genename: PITPNM1
    Top Product
    Discover our top product PITPNM1 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 8000. Western blot: Customer's experiments gave a band at approx 160 kDa in lysates of a MouseMacrophage cell line after 2 μg/mL antibody staining (calculated MW of 130 kDa accordingto NP_004901.1). In ICC the customer found staining of vesicular cytoplasm in the samecell line.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PITPNM1 (Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1))
    别名
    NIR2 (PITPNM1 产品)
    别名
    DRES9 antibody, Mpt-1 antibody, Nir-2 antibody, PITPnm 1 antibody, Pitpnm antibody, R75447 antibody, Rd9 antibody, RdgB antibody, RdgB1 antibody, NIR2 antibody, PITPNM antibody, RDGB antibody, RDGB1 antibody, RDGBA antibody, RDGBA1 antibody, phosphatidylinositol transfer protein membrane associated 1 antibody, phosphatidylinositol transfer protein, membrane-associated 1 antibody, PITPNM1 antibody, Pitpnm1 antibody
    背景
    NIR2 belongs to a family of proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis. A specific Thr residue in the Nir2 PI-transfer domain provides a regulatory site for targeting to lipid droplets. This may affect intracellular lipid trafficking and distribution & explain the dominant effect of the RdgB-T59E mutant on retinal degeneration.Synonyms: DRES9, Membrane-associated phosphatidylinositol transfer protein 1, NIR2, PITPNM, PITPNM1
    基因ID
    9600
    NCBI登录号
    NP_004901
    UniProt
    O00562
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