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PAX8 抗体 (N-Term)

PAX8 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374237
发货至: 中国
  • 抗原 See all PAX8 抗体
    PAX8 (Paired Box 8 (PAX8))
    抗原表位
    • 28
    • 11
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 112
    • 48
    • 45
    • 20
    • 20
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 73
    • 38
    • 1
    山羊
    克隆类型
    • 56
    • 56
    多克隆
    标记
    • 63
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAX8 antibody is un-conjugated
    应用范围
    • 88
    • 36
    • 31
    • 31
    • 26
    • 17
    • 16
    • 12
    • 11
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    PHNSIRSGHG GLN-C
    特异性
    This antibody is expected to recognise all five isoforms of Human PAX8.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from N Terminus of the protein sequence according to NP_003457.1, NP_039245.1, NP_039246.1, NP_039247.1, NP_054698.1. Genename: PAX8
    Top Product
    Discover our top product PAX8 Primary Antibody
  • 应用备注
    Peptide ELISA: Antibody Detection Limit Dilution 1/32000. Immunohistochemistry: 1-2 μg/mL. In paraffin embedded Human Thyroid Gland shows nuclear staining in epithelial cellsaround follicles. A customer found this antibody unsuccessful in Immunohistochemistry onMouse tissues.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
  • Borgogni, Sarchielli, Sottili, Santarlasci, Cosmi, Gelmini, Lombardi, Cantini, Perigli, Luconi, Vannelli, Annunziato, Adorini, Serio, Crescioli: "Elocalcitol inhibits inflammatory responses in human thyroid cells and T cells." in: Endocrinology, Vol. 149, Issue 7, pp. 3626-34, (2008) (PubMed).

  • 抗原
    PAX8 (Paired Box 8 (PAX8))
    别名
    PAX8 (PAX8 产品)
    别名
    PAX8 antibody, XPax-8 antibody, XPax8 antibody, pax-8 antibody, PAX-8 antibody, Pax-8 antibody, paired box 8 antibody, paired box 8 L homeolog antibody, PAX8 antibody, pax8 antibody, Pax8 antibody, pax8.L antibody
    背景
    This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.Synonyms: Paired box protein Pax-8, Pax-8
    基因ID
    7849
    NCBI登录号
    NP_003457
    UniProt
    Q06710
    途径
    Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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