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DAP3 抗体 (C-Term)

DAP3 适用: 人 WB, IF 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374210
发货至: 中国
  • 抗原 See all DAP3 抗体
    DAP3 (Death-Associated Protein 3 (DAP3))
    抗原表位
    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 33
    • 10
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 30
    • 4
    • 1
    山羊
    克隆类型
    • 30
    • 4
    多克隆
    标记
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DAP3 antibody is un-conjugated
    应用范围
    • 35
    • 13
    • 13
    • 9
    • 7
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    NPSLLERHCA YL
    特异性
    This antibody is expected to recognise isoform 1 (NP_387506.1), isoform 2 (NP_001186779.1) and isoform 3 (NP_001186780.1). Reported variants represent identical protein (NP_387506.1, NP_004623.1, NP_001186778.1).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    免疫原
    Peptide from C Terminus of the protein sequence according to NP_387506.1, NP_004623.1 Genename: DAP3
    Top Product
    Discover our top product DAP3 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western blot: 1 - 3 μg/mL. Approx 40-45 kDa band seen in HeLa lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DAP3 (Death-Associated Protein 3 (DAP3))
    别名
    DAP3 / MRPS29 (DAP3 产品)
    别名
    DAP-3 antibody, MRP-S29 antibody, MRPS29 antibody, bMRP-10 antibody, 4921514D13Rik antibody, im:6905684 antibody, death associated protein 3 antibody, DAP3 antibody, Dap3 antibody, dap3 antibody
    背景
    Death Associated Protein 3 (DAP3) is a 46 kDa protein carrying a potential nucleotide binding motif (P-loop) at its N-terminal region. The protein is widely expressed, and the expression is upregulated during membrane-receptor mediated apoptosis. In interferon-gamma and Fas induced apoptosis, DAP3 acts as a positive mediator by functioning downstream of the receptor signaling complex and upstream of the effector caspases. However, the mechanism for its function is largely unknown. Interestingly, the N-terminal 230 amino acid fragment of DAP3 alone protects cells from Fas induced cell death. The same region of DAP3 also serves as a binding site for the glucocorticoid receptor and mediates receptor functions.Synonyms: 28S ribosomal protein S29 mitochondrial, DAP-3, Death-associated protein 3, Ionizing radiation resistance conferring protein, MRP-S29
    基因ID
    7818
    NCBI登录号
    NP_387506
    UniProt
    P51398
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