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TFEB 抗体 (N-Term)

TFEB 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB, IHC (p), ChIP, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374208
发货至: 中国
  • 抗原 See all TFEB 抗体
    TFEB (Transcription Factor EB (TFEB))
    抗原表位
    • 16
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 64
    • 30
    • 26
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, Pig
    宿主
    • 57
    • 6
    • 1
    山羊
    克隆类型
    • 57
    • 6
    多克隆
    标记
    • 40
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFEB antibody is un-conjugated
    应用范围
    • 58
    • 32
    • 14
    • 13
    • 13
    • 13
    • 10
    • 9
    • 8
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Enzyme Immunoassay (EIA)
    序列
    ASRIGLRMQL MRE-C
    特异性
    This antibody detects TFEB at N-term.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine, Porcine and Bovine.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from N Terminus of the protein sequence according to NP_009093.1 Genename: TFEB
    Top Product
    Discover our top product TFEB Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 16000. Western blot: 0.5-2 μg/mL. Approx 50-55 kDa band seen in NIH-3T3 lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TFEB (Transcription Factor EB (TFEB))
    别名
    TFEB (TFEB 产品)
    别名
    TFEB antibody, tcfeb antibody, MGC145796 antibody, alphatfeb antibody, ALPHATFEB antibody, BHLHE35 antibody, TCFEB antibody, Tcfeb antibody, bHLHe35 antibody, transcription factor EB antibody, TFEB antibody, tfeb antibody, Tfeb antibody
    背景
    Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.Synonyms: Transcription factor EB
    基因ID
    7942
    NCBI登录号
    NP_009093
    UniProt
    P19484
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