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FOXP3 抗体 (C-Term)

FOXP3 适用: 人, Pig, 犬 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374156
发货至: 中国
  • 抗原 See all FOXP3 抗体
    FOXP3 (Forkhead Box P3 (FOXP3))
    抗原表位
    • 23
    • 16
    • 15
    • 10
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 155
    • 113
    • 46
    • 25
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Pig, 犬
    宿主
    • 116
    • 58
    • 11
    • 2
    山羊
    克隆类型
    • 116
    • 71
    多克隆
    标记
    • 89
    • 18
    • 12
    • 12
    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This FOXP3 antibody is un-conjugated
    应用范围
    • 133
    • 83
    • 70
    • 38
    • 37
    • 27
    • 27
    • 19
    • 18
    • 17
    • 9
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    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    SQRPSRCSNP TPGP
    特异性
    This antibody is expected to recognize both reported isoforms (NP_054728.2 and NP_001107849.1).
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog) and Pig.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from C-Terminus of the protein sequence according to NP_054728.2, NP_001107849.1. Genename: FOXP3
    Top Product
    Discover our top product FOXP3 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit Dilution: 1/16000. Immunohistochemistry: 0.3-1 μg/mL. In paraffin embedded Human Tonsil, stains nuclei ofsome cells in the interfollicular area.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FOXP3 (Forkhead Box P3 (FOXP3))
    别名
    FOXP3 (FOXP3 产品)
    别名
    foxp3 antibody, FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, PIDX antibody, XPID antibody, JM2 antibody, scurfin antibody, sf antibody, RGD1562112 antibody, forkhead box P3 antibody, forkhead box P3a antibody, forkhead box P3 L homeolog antibody, FOXP3 antibody, foxp3a antibody, foxp3 antibody, foxp3.L antibody, Foxp3 antibody
    背景
    FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin
    基因ID
    50943
    NCBI登录号
    NP_054728
    UniProt
    Q9BZS1
    途径
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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