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STAT3 抗体 (C-Term, Isoform 1)

STAT3 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 WB, IF, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374087
发货至: 中国
  • 抗原 See all STAT3 抗体
    STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
    抗原表位
    • 90
    • 54
    • 27
    • 8
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    C-Term, Isoform 1
    适用
    • 277
    • 142
    • 136
    • 38
    • 25
    • 25
    • 22
    • 17
    • 17
    • 6
    • 4
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    • 1
    人, 小鼠, 大鼠, Cow, Pig, 犬
    宿主
    • 228
    • 58
    • 4
    • 2
    • 1
    • 1
    山羊
    克隆类型
    • 196
    • 96
    多克隆
    标记
    • 164
    • 23
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    • 10
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    • 9
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    • 3
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    • 1
    • 1
    This STAT3 antibody is un-conjugated
    应用范围
    • 218
    • 110
    • 75
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    • 15
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    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    DMELTSECAT SPM
    特异性
    This antibody is expected to recognize Isoform 1 (NP_644805.1) and Isoform 2 (NP_003141.2).
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog), Pig and Bovine.
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Peptide from C-Terminus of the protein sequence according to NP_003141.2, NP_644805.1. Genename: STAT3
    Top Product
    Discover our top product STAT3 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/128000. Western blot: 1-3 μg/mL. Approx.90 kDa band observed in lysates of NIH3T3 (calculatedMW of 88.0 kDa according to NP_644805.1 and of 88.1 according to NP_003141.2). Immunohistochemistry: Rommended overnight staining at 10 μg/mL (See picture). Stainsmouse thymic medulla and not the cortex.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
  • 抗原
    STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
    别名
    STAT3 (STAT3 产品)
    别名
    1110034C02Rik antibody, AW109958 antibody, Aprf antibody, APRF antibody, HIES antibody, Xstat3 antibody, aprf antibody, hies antibody, stat3 antibody, wu:fc15d02 antibody, wu:fl59g06 antibody, z-Stat3 antibody, signal transducer and activator of transcription 3 antibody, signal transduction and activation of transcription 3 antibody, signal transducer and activator of transcription 3, gene 1 L homeolog antibody, signal transducer and activator of transcription 3 (acute-phase response factor) antibody, STAT3 antibody, stat3 antibody, Stat3 antibody, stat3.1.L antibody
    背景
    The STAT3 protein is expressed in most cell types and is activated by multiple cytokines and growth factors including: IFNa, IL10, IL6, IL11, IL12, IL2, EGF, among others. STAT3 beta appears to be activated by both EGF and IL6, but STAT3 alpha is only activated by EGF. STAT3 binds to DNA as either a homodimer or as a heterodimer with STAT1. STAT3 interacts with the APRE acute phase response element) and SIE (csis inducible element). STAT4, predominantly expressed in testis and myeloid cells, is activated by ILl2. STAT5 is activated by prolactin and IL3. STAT6 participates in signaling pathways mediated by IL4.Synonyms: APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3
    基因ID
    6774
    NCBI登录号
    NP_003141
    UniProt
    P40763
    途径
    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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