UCHL1 抗体
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- 抗原 See all UCHL1 抗体
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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适用
- 人, 大鼠, 小鼠, Cow, 哺乳动物
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This UCHL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Specific for the the ~24 kDa UCHL1 protein.
- 交叉反应 （详细）
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Species reactivity (expected):Mamalia.
Species reactivity (tested):Bovine, Human, Mouse and Rat. - 纯化方法
- Ig Fraction
- 免疫原
- Recombinant full length human UCHL1 purified from E. coli.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UCHL1 Primary Antibody
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anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibody
UCHL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibodyUCHL1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibodyUCHL1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyUCHL1 适用: 人, 大鼠 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal rUCHL1-775 unconjugated Recombinant Antibody
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 59-223) antibodyUCHL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 187-216), (C-Term) antibodyUCHL1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB7379 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyMicroarray verified UCHL1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB215939 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyUCHL1 适用: 人, 大鼠, 小鼠, Cow, Pig WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal 31A3 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 1-223) antibodyUCHL1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B8-4D2 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 1-220) antibodyUCHL1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
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- 应用备注
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Western blotting: 1/2,500. Immunofluorescence: 1/500. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- 抗原
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- 别名
- UCHL1 / PGP9.5 (UCHL1 产品)
- 别名
- PARK5 antibody, PGP 9.5 antibody, PGP9.5 antibody, PGP95 antibody, Uch-L1 antibody, UCH-L1 antibody, UCHL1 antibody, cb358 antibody, wu:fc55h08 antibody, park5 antibody, pgp9.5 antibody, uch-l1 antibody, MGC132191 antibody, uchl1 antibody, AW822034 antibody, C88048 antibody, R75593 antibody, UCHL-1 antibody, gad antibody, ubiquitin C-terminal hydrolase L1 antibody, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) antibody, ubiquitin C-terminal hydrolase L1 L homeolog antibody, ubiquitin carboxyl-terminal esterase L1 antibody, ubiquitin carboxy-terminal hydrolase L1 antibody, UCHL1 antibody, uchl1 antibody, uchl1.L antibody, LOC100304750 antibody, Uchl1 antibody
- 背景
- Ubiquitin C-terminal hydrolase 1 (UCHL1) is also known as ubiquitin carboxyl esterase L1, ubiquitin thiolesterase, neuron-specific protein PGP9.5 and Park5. It was originally identified as a major component of the neuronal cytoplasm from 2-dimensional gel analysis of brain tissues, and was given the name PGP9.5 (1). It was later found that ubiquitin C-terminal hydrolase enzyme activity was associated with the PGP9.5 protein (2). The ubiquitin C-terminal hydrolases cleave ubiquitin from other molecules. Regulation of the ubiquitin pathway is very important and many disease states are associated with defects in this pathway. Genetic knockout of UCHL1 in mice results in a motor neuron degeneration similar to the spontaneous gracile axonal dystrophy (gad) mutant mice (3). Point mutations in the UCHL1 gene are associated with some forms of human Parkinson's disease (4). Since UCHL1 is heavily expressed in neurons, it is released in large amounts following injury or degeneration, so the detection of UCHL1 in CSF and other bodily fluids can be used as a biomarker.Synonyms: Neuron cytoplasmic protein 9.5, PGP 9.5, UCH-L1, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Ubiquitin thioesterase L1
- 基因ID
- 7345
- NCBI登录号
- NP_004172
- UniProt
- P09936
- 途径
- Feeding Behaviour
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