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MAP2K5 抗体 (pSer311, pThr315)

MAP2K5 适用: 人, 小鼠, 大鼠, 犬, 小鸡, Cow, 斑马鱼, 非洲爪蟾, Non-Human Primate WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372667
发货至: 中国
  • 抗原 See all MAP2K5 抗体
    MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
    抗原表位
    • 28
    • 28
    • 16
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    • 15
    • 9
    • 9
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer311, pThr315
    适用
    • 129
    • 58
    • 54
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 小鸡, Cow, 斑马鱼, 非洲爪蟾, Non-Human Primate
    宿主
    • 141
    • 6
    克隆类型
    • 133
    • 14
    多克隆
    标记
    • 43
    • 11
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    This MAP2K5 antibody is un-conjugated
    应用范围
    • 112
    • 66
    • 65
    • 50
    • 19
    • 15
    • 14
    • 12
    • 8
    • 3
    • 1
    • 1
    • 1
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    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody is specific for the ~49k MEK5 protein phosphorylated at Ser311, Thr315. Immunolabeling of the MEK5 band is blocked by preadsorption with the phospho-peptide used as antigen but not be the corresponding dephospho-peptide.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Human, Chicken, Bovine, Canine, non-Human Primates, Xenopus, and Zebrafish.
    Species reactivity (tested):Rat.
    纯化方法
    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser311, Thr315 of MEK5.
    亚型
    IgG
    Top Product
    Discover our top product MAP2K5 Primary Antibody
  • 应用备注
    Western blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
    别名
    MAP2K5 (MAP2K5 产品)
    别名
    Mek5 antibody, HsT17454 antibody, MAPKK5 antibody, MEK5 antibody, PRKMK5 antibody, AI324775 antibody, AI428457 antibody, Mapkk5 antibody, Prkmk5 antibody, fb73f02 antibody, wu:fb73f02 antibody, zgc:172137 antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 antibody, ATMAP2K_ALPHA antibody, ATMEK5 antibody, ATMKK5 antibody, MAP KINASE KINASE 5 antibody, MAP kinase kinase 5 antibody, MAP2K_A antibody, mitogen activated protein kinase kinase 5 antibody, mitogen-activated protein kinase kinase 5 antibody, mitogen-activated protein kinase kinase 5 L homeolog antibody, MAP kinase kinase 5 antibody, Map2k5 antibody, MAP2K5 antibody, map2k5 antibody, map2k5.L antibody, MKK5 antibody
    背景
    MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 (Zhou et al., 1995) whereas MEK5 itself is regulated by MEKK3 (Chao et al., 1999). An important link between MEK5 and metastatic prostrate cancer has been demonstrated (Mehta et.al., 2003). Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation (Cameron et al., 2004).Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MEK5, MKK5
    基因ID
    29568
    NCBI登录号
    NP_001029159
    UniProt
    Q62862
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway
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