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HAVCR1 抗体 (AA 200-300)

HAVCR1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372415
发货至: 中国
  • 抗原 See all HAVCR1 抗体
    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
    抗原表位
    • 12
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-300
    适用
    • 99
    • 48
    • 34
    • 6
    • 6
    • 5
    人, 小鼠
    宿主
    • 102
    • 24
    • 5
    • 2
    克隆类型
    • 105
    • 28
    • 1
    多克隆
    标记
    • 65
    • 15
    • 14
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HAVCR1 antibody is un-conjugated
    应用范围
    • 93
    • 41
    • 32
    • 17
    • 16
    • 12
    • 11
    • 11
    • 11
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognizes Hepatitis A Virus Cellular Receptor 1 (HAVCR1).
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Protein G Chromatography.
    免疫原
    Synthetic peptide corresponding amino acids 200-300 of human HAVCR1.
    亚型
    IgG
    Top Product
    Discover our top product HAVCR1 Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections: 2.5-5.0 μg/mL. Western blot: 1-3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
    别名
    TIMD1 / HAVCR1 (HAVCR1 产品)
    别名
    HAVCR antibody, HAVCR-1 antibody, KIM-1 antibody, KIM1 antibody, TIM antibody, TIM-1 antibody, TIM1 antibody, TIMD-1 antibody, TIMD1 antibody, Kim1 antibody, HAVCR1 antibody, LOC100226241 antibody, AI503787 antibody, Tim1 antibody, Timd1 antibody, hepatitis A virus cellular receptor 1 antibody, hepatitis A virus cellular receptor 1 homolog antibody, HAVCR1 antibody, Havcr1 antibody, LOC100226241 antibody
    物质类
    Virus
    背景
    HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epithelium in Kidneys. HAVCR1 has shown to be upregulated in renal carcinomas, suggesting its role in tumor progression and metastasis.Synonyms: HAVCR-1, Hepatitis A virus cellular receptor 1, T cell immunoglobulin and mucin domain-containing protein 1, T cell membrane protein 1, TIM-1, TIM1, TIMD-1
    基因ID
    26762
    NCBI登录号
    NP_001092884
    UniProt
    Q96D42
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