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BCL2L1 抗体 (Biotin)

BCL2L1 适用: 人, 小鼠, 大鼠 FACS 宿主: 小鼠 Monoclonal 7B2-5 Biotin
产品编号 ABIN371609
发货至: 中国
  • 抗原 See all BCL2L1 抗体
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    适用
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    人, 小鼠, 大鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This BCL2L1 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognizes Bcl-xL.
    产品特性
    Synonyms: Bcl2-L-1, BCL2L1, BCL2L, BCLX, Bcl-x, bcl-xL, bcl-xS, Bcl-2-like protein 1
    免疫原
    Recombinant Bcl-xS.
    克隆位点
    7B2-5
    亚型
    IgG3
    Top Product
    Discover our top product BCL2L1 Primary Antibody
  • 应用备注
    Flow Cytometry: < / = 3 μg/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    别名
    Bcl-2-Like 1 (BCL2L1 产品)
    别名
    BCL-XL/S antibody, BCL2L antibody, BCLX antibody, BCLXL antibody, BCLXS antibody, Bcl-X antibody, PPP1R52 antibody, bcl-xL antibody, bcl-xS antibody, Bcl(X)L antibody, Bcl-XL antibody, Bcl-Xs antibody, Bcl2l antibody, BclX antibody, bcl-x antibody, Bcl-xl antibody, Bclx antibody, bcl-X antibody, Bcl-xL antibody, BCL-XL antibody, BCL2L1 antibody, bcl-XL antibody, bcl-x(l) antibody, bcl-xl/s antibody, bcl-xs antibody, bcl2l antibody, bclx antibody, bclxl antibody, xR11 antibody, bcl-xl antibody, blp1 antibody, cb1021 antibody, zfBLP1 antibody, BCL2 like 1 antibody, BCL2-like 1 antibody, Bcl2-like 1 antibody, BCL2-like 1 L homeolog antibody, bcl2-like 1 antibody, BCL2L1 antibody, Bcl2l1 antibody, bcl2l1 antibody, bcl2l1.L antibody
    背景
    Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. (Ref.1) It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. (Ref.2) Bcl-2 and one of its homologues, Bcl-xL, protect cells from apoptosis (Ref.3,4) while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis. (Ref.5-8) Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. (Ref.9-13) In contrast, Bad and Bax inhibit the protective functions of Bcl-xL and Bcl-2, respectively. Although heterodimerization between Bcl-xL/Bad and Bcl-2/Bax was originally thought to be essential for the differential anti-apoptotic activity of Bcl-xL and Bcl-2. (Ref.5,14) Other results suggest that the formation of heterodimers may not be necessary for this death-repressing activity. (Ref.15,16)Synonyms: BCL2L, BCL2L1, BCLX, Bcl-2-like protein 1, Bcl-x, Bcl2-L-1, bcl-xL, bcl-xS
    UniProt
    Q07817
    途径
    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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