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LAMP2 抗体

LAMP2 适用: 人 WB, FACS, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal H4B4 unconjugated
产品编号 ABIN371603
发货至: 中国
  • 抗原 See all LAMP2 抗体
    LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This LAMP2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognizes Human CD107b/LAMP-2. Other species not tested.
    产品特性
    Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2
    纯化方法
    Purified
    克隆位点
    H4B4
    亚型
    IgG1
    Top Product
    Discover our top product LAMP2 Primary Antibody
  • 应用备注
    Flow Cytometry: < / = 1 μg/10^6 cells. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    100 mM Borate Buffered Saline, pH 8.2 without preservatives.
    储存液
    Without preservative
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
    别名
    CD107b / LAMP2 (LAMP2 产品)
    别名
    CD107b antibody, LAMP-2 antibody, LAMPB antibody, LGP110 antibody, Lamp-2 antibody, Lamp-2a antibody, Lamp-2b antibody, Lamp-2c antibody, Mac3 antibody, cd107b antibody, lamp-2 antibody, lampb antibody, LAMP2 antibody, lamp2 antibody, DKFZp459J126 antibody, LGP-B antibody, sb:cb587 antibody, wu:fb14a06 antibody, zgc:103532 antibody, lysosomal associated membrane protein 2 antibody, lysosomal-associated membrane protein 2 antibody, lysosomal-associated membrane protein 2 S homeolog antibody, lysosomal membrane glycoprotein 2 antibody, LAMP2 antibody, Lamp2 antibody, lamp2.S antibody, lamp2 antibody
    背景
    CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107b is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-2 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential, where they may increase adhesion to extracellular matrix and endothelium. (Ref.1-7)Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2
    基因ID
    3920
    UniProt
    P13473
    途径
    Autophagy
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