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LAMP1 抗体 (PE)

LAMP1 适用: 人 FACS 宿主: 小鼠 Monoclonal H4A3 PE
产品编号 ABIN371599
发货至: 中国
  • 抗原 See all LAMP1 抗体
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This LAMP1 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognizes CD107a/LAMP-1.
    产品特性
    Synonyms: LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1, CD107Antigen-like Family Member A
    克隆位点
    H4A3
    亚型
    IgG1
    Top Product
    Discover our top product LAMP1 Primary Antibody
  • 应用备注
    Flow Cytometry: 10 μL/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    别名
    CD107a / LAMP1 (LAMP1 产品)
    别名
    CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
    背景
    CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential, where they may increase adhesion to extracellular matrix and endothelium. (Ref.1-7)Synonyms: CD107 Antigen-like Family Member A, LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1
    基因ID
    3916
    UniProt
    P11279
    途径
    Autophagy
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