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小鼠 anti-小鸡 IgM Antibody (Biotin)

FACS Monoclonal M-1 IgG2b Biotin
产品编号 ABIN371377
发货至: 中国
  • 抗原 See all IgM products
    IgM
    适用
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    小鸡
    宿主
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    小鼠
    克隆类型
    • 496
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    单克隆
    标记
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    Biotin
    应用范围
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    Flow Cytometry (FACS)
    克隆位点
    M-1
    亚型
    IgG2b
  • 应用备注
    Flow Cytometry: < / = 1 μg/10^6 cells.

    Other applications not tested.
    Otimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -28 °C for longer.
  • 抗原
    IgM
    Abstract
    IgM 产品
    物质类
    Antibody
    背景
    IgM normally constitutes about 10 % of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease.Synonyms: Chicken Immunoglobulin M
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