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CD72 抗体

CD72 适用: 小鼠 FACS, Func 宿主: 小鼠 Monoclonal 10-1-D-2 unconjugated
产品编号 ABIN371001
发货至: 中国
  • 抗原 See all CD72 抗体
    CD72 (CD72 Molecule (CD72))
    适用
    • 46
    • 18
    • 1
    小鼠
    宿主
    • 37
    • 19
    • 1
    小鼠
    克隆类型
    • 37
    • 20
    单克隆
    标记
    • 25
    • 7
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD72 antibody is un-conjugated
    应用范围
    • 29
    • 24
    • 21
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    This antibody recognises CD72.1/Lyb-2.1 (Mr. 45 kDa). It blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (Ref.1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72. (Ref.1-5)
    产品特性
    Synonyms: Lyb-2, Ly-32, Ly32, B-Cell marker, B-cell differentiation antigen CD72, Lymphocyte antigen32
    纯化方法
    Purified
    免疫原
    DBA/2 mouse spleen cells. (Ref. 1)
    克隆位点
    10-1-D-2
    亚型
    IgG2b
    Top Product
    Discover our top product CD72 Primary Antibody
  • 应用备注
    Flow Cytometry. (Ref.1,2)Functional Assays: In vitro blocking and proliferation assays. (Ref.2,3)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD72 (CD72 Molecule (CD72))
    别名
    CD72 (CD72 产品)
    别名
    CD72c antibody, Ly-19 antibody, Ly-32 antibody, Ly-m19 antibody, Lyb-2 antibody, CD72b antibody, LYB2 antibody, CD72 antigen antibody, CD72 molecule antibody, Cd72 antibody, CD72 antibody
    背景
    Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (Ref.1,2)Synonyms: B-Cell marker, B-cell differentiation antigen CD72, Ly-32, Ly32, Lyb-2, Lymphocyte antigen 32
    基因ID
    100504743
    UniProt
    P21855
    途径
    BCR Signaling
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