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FOXO1 抗体 (AA 254-258)

Name: FOXO1 抗体 (AA 254-258)
SKU: ABIN362738
Availability: OutOfStock

FOXO1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

(1 reference)

产品编号 ABIN362738

发货至: 中国

Datasheet as PDF

抗原 See all FOXO1 抗体

FOXO1 (Forkhead Box O1 (FOXO1))
抗原表位
25

21

18

18

17

16

16

16

11

10

7

6

6

4

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 254-258
适用
230

161

150

48

30

25

18

11

9

8

6

4

2

1

1
人, 小鼠, 大鼠
宿主
211

21

1

1
兔
Compatible Secondaries
克隆类型
204

30
多克隆
标记
104

11

10

9

9

9

9

9

9

9

7

7

7

7

7

5

1

1

1

1

1

1
This FOXO1 antibody is un-conjugated
应用范围
197

91

78

66

57

56

44

32

20

20

8

6

5

3

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

特异性

The antibody detects endogenous level of total FKHR protein.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

免疫原

Peptide sequence around AA 254-258 (A-A-S-M-D) derived from Human FKHR, FOXO1A. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

亚型

IgG

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应用备注

Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Ma, Li, Wang, Gong, Zhang, Li, Ji, Liu, Chen, Xiang: "Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways." in: Regulatory peptides, Vol. 181, pp. 9-16, (2013) (PubMed).
抗原

FOXO1 (Forkhead Box O1 (FOXO1))

别名

FKHR (FOXO1 产品)

别名

FKH1 antibody, FKHR antibody, FOXO1A antibody, FoxO1a.1 antibody, foxo1 antibody, zgc:153388 antibody, Fkhr antibody, Foxo1a antibody, AI876417 antibody, Afxh antibody, Fkhr1 antibody, fkh1 antibody, fkhr antibody, foxo1a antibody, xFoxO1 antibody, FoxO1A antibody, foxo1a.2 antibody, forkhead box O1 antibody, forkhead box O1 a antibody, forkhead box O1 L homeolog antibody, forkhead box O1 b antibody, FOXO1 antibody, foxo1a antibody, Foxo1 antibody, foxo1 antibody, foxo1.L antibody, foxo1b antibody

背景

FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14

分子量

78-82 kDa

NCBI登录号

NP_002006

UniProt

Q12778

途径

PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling