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MAP2K3 抗体 (AA 187-191)

MAP2K3 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362698
发货至: 中国
  • 抗原 See all MAP2K3 抗体
    MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
    抗原表位
    • 25
    • 19
    • 15
    • 15
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 187-191
    适用
    • 139
    • 101
    • 80
    • 11
    • 10
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 142
    • 12
    克隆类型
    • 129
    • 25
    多克隆
    标记
    • 70
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This MAP2K3 antibody is un-conjugated
    应用范围
    • 120
    • 49
    • 40
    • 39
    • 32
    • 28
    • 20
    • 9
    • 9
    • 8
    • 8
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    特异性
    The antibody detects endogenous level of total MKK3 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    免疫原
    Peptide sequence around AA 187-191 (V-D-S-V-A) derived from Human MKK3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    亚型
    IgG
    Top Product
    Discover our top product MAP2K3 Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
    别名
    MKK3 (MAP2K3 产品)
    别名
    MAPKK3 antibody, MEK3 antibody, MKK3 antibody, PRKMK3 antibody, SAPKK-2 antibody, SAPKK2 antibody, AW212142 antibody, Prkmk3 antibody, mMKK3b antibody, Mkk3 antibody, mitogen-activated protein kinase kinase 3 antibody, mitogen activated protein kinase kinase 3 antibody, MAP kinase activator XMEK3 antibody, MAP2K3 antibody, Map2k3 antibody, map2k3 antibody
    背景
    MEK3 belongs to MAPKK family. This kinase is activated by mitogenic and environmental stress, and participates in the MAPK-mediated signaling cascade. It phosphorylates and thus activates p38. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of Ras oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of p38, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis.
    分子量
    40 kDa
    NCBI登录号
    NP_002747
    UniProt
    P46734
    途径
    MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
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