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EIF2A 抗体 (pSer49)

EIF2A 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362446
发货至: 中国
  • 抗原 See all EIF2A 抗体
    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
    抗原表位
    • 17
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer49
    适用
    • 82
    • 42
    • 41
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 68
    • 15
    克隆类型
    • 66
    • 17
    多克隆
    标记
    • 44
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF2A antibody is un-conjugated
    应用范围
    • 66
    • 35
    • 33
    • 33
    • 14
    • 13
    • 13
    • 11
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    特异性
    The antibody detects endogenous level of eIF2a only when phosphorylated at Serine 49.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    免疫原
    Peptide sequence around phosphorylation site of pSer49 (L-L-S (p) -E-L) derived from Human eIF2a. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    亚型
    IgG
    Top Product
    Discover our top product EIF2A Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
    别名
    eIF2alpha (EIF2A 产品)
    别名
    ATEIF2-A2 antibody, EIF2-A2 antibody, eukaryotic translation initiation factor 2 alpha subunit antibody, EIF-2A antibody, MST089 antibody, MSTP004 antibody, MSTP089 antibody, D030048D22 antibody, D3Ertd194e antibody, im:7145971 antibody, zgc:110460 antibody, DDBDRAFT_0185936 antibody, DDBDRAFT_0234177 antibody, DDB_0185936 antibody, DDB_0234177 antibody, Eif2a antibody, eif2a antibody, eif2alpha antibody, EIF2A antibody, CG9946 antibody, Dmel\\CG9946 antibody, Eif2alpha antibody, IF2A_DROME antibody, M(1)14C antibody, M(1)19-153 antibody, M(1)8e3-10 antibody, deIF2alpha antibody, eIF-2 antibody, eIF-2 a antibody, eIF-2 alpha antibody, eIF2 alpha antibody, eIF2-alpha antibody, eIF2a antibody, eIF2alpha antibody, eiF-2alpha antibody, elF2alpha antibody, l(1)14Cf antibody, l(1)19-153 antibody, eukaryotic translation initiation factor 2 alpha subunit antibody, eukaryotic translation initiation factor 2A antibody, eukaryotic translation initiation factor 2A, 65kDa antibody, eukaryotic translation initiation factor 2A S homeolog antibody, eukaryotic translation initiation factor antibody, eukaryotic translation Initiation Factor 2alpha antibody, EIF2 ALPHA antibody, EIF2A antibody, Eif2a antibody, eif2a antibody, eIF2a antibody, eif2a.S antibody, eif2A antibody, eIF-2alpha antibody
    背景
    Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
    分子量
    38 kDa
    NCBI登录号
    NP_004085
    UniProt
    P05198
    途径
    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
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