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PKC delta 抗体 (pSer645)

Name: PKC delta 抗体 (pSer645)
SKU: ABIN362384
Availability: OutOfStock

PKCd 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

(1 reference)

产品编号 ABIN362384

发货至: 中国

Datasheet as PDF

抗原 See all PKC delta (PKCd) 抗体

PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
抗原表位
22

20

16

15

15

15

15

14

11

8

8

6

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer645
适用
203

152

150

8

3

3

2

2

2

1

1
人, 小鼠, 大鼠
宿主
214

9
兔
Compatible Secondaries
克隆类型
203

20
多克隆
标记
92

14

12

10

9

9

9

9

9

9

7

6

6

6

6

6

4
This PKC delta antibody is un-conjugated
应用范围
158

86

81

80

49

41

36

23

20

13

5

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

特异性

The antibody detects endogenous level of PKCd only when phosphorylated at serine 645.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

免疫原

Peptide sequence around phosphorylation site of pSer645 (R-L-S (p) -Y-S) derived from Human PKCd. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

亚型

IgG

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PKCd 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E12 unconjugated

anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibody
PKCd 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6A2 unconjugated

anti-Protein Kinase C, delta (PKCd) (C-Term) antibody
PKCd 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (pTyr313) antibody
PKCd 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (N-Term) antibody
PKCd 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (pTyr64) antibody
PKCd 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (pSer645) antibody
PKCd 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (pSer645) antibody
PKCd 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, delta (PKCd) (Thr292) antibody
PKCd 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Uenoyama, Ogata, Nakanishi, Kanazawa, Hiroi, Tominaga, Seo, Matsui, Kawai, Suzuki: "Protein kinase C mRNA and protein expressions in hypobaric hypoxia-induced cardiac hypertrophy in rats." in: Acta physiologica (Oxford, England), Vol. 198, Issue 4, pp. 431-40, (2010) (PubMed).
抗原

PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

别名

PKCdelta (PKCd 产品)

别名

MAY1 antibody, PKCD antibody, nPKC-delta antibody, AI385711 antibody, D14Ertd420e antibody, PKC[d] antibody, PKCdelta antibody, Pkcd antibody, fb09d10 antibody, fv43b11 antibody, prkcd antibody, wu:fb09d10 antibody, wu:fv43b11 antibody, zgc:56558 antibody, PKC-delta antibody, may1 antibody, npkc-delta antibody, pkc-delta2 antibody, pkcd antibody, tpa-1 antibody, protein kinase C delta antibody, protein kinase C, delta antibody, protein kinase C, delta a antibody, protein kinase C delta L homeolog antibody, PRKCD antibody, Prkcd antibody, prkcda antibody, prkcd.L antibody, prkcd antibody

背景

This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

分子量

78 kDa

NCBI登录号

NP_006245

UniProt

Q05655

途径

Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism