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KIT 抗体 (pTyr721)

KIT 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362294
发货至: 中国
  • 抗原 See all KIT 抗体
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    抗原表位
    • 55
    • 55
    • 35
    • 28
    • 23
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    • 21
    • 16
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    pTyr721
    适用
    • 669
    • 227
    • 66
    • 29
    • 28
    • 28
    • 17
    • 13
    • 5
    • 4
    • 2
    • 2
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 602
    • 101
    • 34
    • 2
    • 1
    克隆类型
    • 594
    • 146
    • 1
    多克隆
    标记
    • 227
    • 80
    • 77
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    • 60
    • 60
    • 13
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This KIT antibody is un-conjugated
    应用范围
    • 430
    • 391
    • 287
    • 147
    • 91
    • 91
    • 65
    • 48
    • 46
    • 46
    • 30
    • 25
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody detects endogenous level of c-Kit only when phosphorylated at tyrosine 721.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    免疫原
    Peptide sequence around phosphorylation site of pTyr721 (N-E-Y (p) -M-D) derived from Human c-Kit. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    亚型
    IgG
    Top Product
    Discover our top product KIT Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Gao, Lin, Gao, Li, Wang, Yu: "MicroRNA-193b regulates c-Kit proto-oncogene and represses cell proliferation in acute myeloid leukemia." in: Leukemia research, Vol. 35, Issue 9, pp. 1226-32, (2011) (PubMed).

  • 抗原
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    别名
    c-Kit (KIT 产品)
    别名
    C-Kit antibody, CD117 antibody, PBT antibody, SCFR antibody, Bs antibody, Fdc antibody, Gsfsco1 antibody, Gsfsco5 antibody, Gsfsow3 antibody, SCO1 antibody, SCO5 antibody, SOW3 antibody, Ssm antibody, Tr-kit antibody, W antibody, c-KIT antibody, c-kit antibody, MGF antibody, KIT antibody, C-KIT antibody, kit antibody, receptor antibody, sparse antibody, Xkl-1 antibody, kit-a antibody, kit-b antibody, kl1-A antibody, krk1 antibody, pbt antibody, scfr antibody, KIT proto-oncogene receptor tyrosine kinase antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antibody, KIT proto-oncogene receptor tyrosine kinase S homeolog antibody, KIT antibody, Kit antibody, kita antibody, kit antibody, kit.S antibody
    背景
    This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)
    分子量
    145 kDa
    NCBI登录号
    NP_000213
    UniProt
    P10721
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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