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LIM Domain Kinase 1 抗体 (pThr508)

LIMK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362108
发货至: 中国
  • 抗原 See all LIM Domain Kinase 1 (LIMK1) 抗体
    LIM Domain Kinase 1 (LIMK1)
    抗原表位
    • 24
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr508
    适用
    • 102
    • 81
    • 76
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 102
    • 15
    • 3
    克隆类型
    • 106
    • 14
    多克隆
    标记
    • 53
    • 10
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This LIM Domain Kinase 1 antibody is un-conjugated
    应用范围
    • 84
    • 51
    • 26
    • 26
    • 24
    • 19
    • 10
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    特异性
    The antibody detects endogenous level of LIMK1 only when phosphorylated at threonine 508.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    免疫原
    Peptide sequence around phosphorylation site of pThr508 (R-Y-T (p) -V-V) derived from Human LIMK1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    亚型
    IgG
    Top Product
    Discover our top product LIMK1 Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Li, Ke, Li, Liu, Zhu, Li: "DGCR6L, a novel PAK4 interaction protein, regulates PAK4-mediated migration of human gastric cancer cell via LIMK1." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 1, pp. 70-9, (2009) (PubMed).

  • 抗原
    LIM Domain Kinase 1 (LIMK1)
    别名
    LIMK1 (LIMK1 产品)
    别名
    limk1 antibody, xlimk1 antibody, GB16654 antibody, LIMK1 antibody, LIMK antibody, LIMK-1 antibody, LIM domain kinase 1 antibody, LIM domain kinase 1a antibody, LIM domain kinase 1 L homeolog antibody, LIM-domain containing, protein kinase antibody, LIMK1 antibody, limk1a antibody, limk1 antibody, CpipJ_CPIJ000717 antibody, LOC413152 antibody, Limk1 antibody, limk1.L antibody
    背景
    Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. May be involved in brain development.
    分子量
    72 kDa
    NCBI登录号
    NP_002305
    UniProt
    P53667
    途径
    Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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