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- 抗原 See all CRYAA 抗体
- CRYAA (Crystallin, alpha A (CRYAA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CRYAA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~20 kDa. Does not cross-react with αB-crystallin, βL-crystallin, ΒH- crystallin, γ-crystallin, HSP25, HSP27 or HSP47 proteins.
- 交叉反应
- Cow, 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Native Alpha Crystallin
- 克隆位点
- 1H3-B8
- 亚型
- IgG1
- Top Product
- Discover our top product CRYAA Primary Antibody
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anti-Crystallin, alpha A (CRYAA) antibody
CRYAA 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Crystallin, alpha A (CRYAA) (AA 1-173) antibodyCRYAA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, alpha A (CRYAA) (AA 77-106) antibodyCRYAA 适用: 人 WB 宿主: 兔 Polyclonal RB28544 unconjugated
anti-Crystallin, alpha A (CRYAA) (AA 1-173) antibodyCRYAA 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal c9F2 unconjugated
anti-Crystallin, alpha A (CRYAA) antibodyCRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 unconjugated
anti-Crystallin, alpha A (CRYAA) antibody (HRP)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 HRP
anti-Crystallin, alpha A (CRYAA) antibody (FITC)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 FITC
anti-Crystallin, alpha A (CRYAA) antibody (Alkaline Phosphatase (AP))CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 Alkaline Phosphatase (AP)
anti-Crystallin, alpha A (CRYAA) antibody (Biotin)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 Biotin
anti-Crystallin, alpha A (CRYAA) antibody (PE)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 PE
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- 应用备注
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- WB (1:2000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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0.5 μg/ml was sufficient for detection of 100 ng purified alphaA crystalline by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.2, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- CRYAA (Crystallin, alpha A (CRYAA))
- 别名
- Alpha A Crystallin (CRYAA 产品)
- 别名
- CRYA1 antibody, CTRCT9 antibody, HSPB4 antibody, AI323437 antibody, Acry-1 antibody, Crya-1 antibody, Crya1 antibody, DAcry-1 antibody, lop18 antibody, alpha-a-crystallin antibody, cryaa-A antibody, CRYAA antibody, wu:fc06h04 antibody, zgc:92036 antibody, HspB4 antibody, crystallin alpha A antibody, crystallin, alpha A antibody, alphaA-crystallin antibody, alpha-crystallin A chain-like antibody, crystallin alpha A S homeolog antibody, alpha-crystallin A chain antibody, CRYAA antibody, Cryaa antibody, CpipJ_CPIJ005646 antibody, cryaa antibody, LOC100384978 antibody, cryaa.S antibody, LOC458589 antibody, LOC102724652 antibody
- 背景
- The alpha-crystallins are major water-soluble lens structural proteins of the vertebrate eye that are related to the small heat shock protein family. The alpha-crystallins possess structural and functional similarities with HSP25 and HSP27 (1). Mammalian lens cystallins are divided into alpha, beta and gamma families. Alpha and beta families are further divided into acidic and basic groups (Alpha-A and Alpha-B respectively). In the lens, alpha-crystallin primarily functions to maintain proper refractive index, however it can also function as a molecular chaperone that binds to the denatured proteins, keeping them in solution and thereby maintaining the translucency of the lens. When cellular stress occurs, alpha-crystallin enters its' phosphorylated state and may serve a structural control function and play a role in protein maintenance (2). In addition to their interaction with proteins, alpha-crystallins also interact with native molecules such as membrane proteins, Golgi matrix protein, structural proteins, nuclear proteins and DNA (3, 4, 5, 6, and 7). Two other functions are an autokinase activity and participation in the intracellular architecture, and it has also been proven that both alpha-A and B prevent apoptosis by inhibiting caspases (8).
- 基因ID
- 1409
- NCBI登录号
- NP_000385
- UniProt
- P02489
- 途径
- M Phase
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