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MAPK7 抗体 (C-Term)

MAPK7 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN359634
发货至: 中国
  • 抗原 See all MAPK7 抗体
    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
    抗原表位
    • 16
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    • 3
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    C-Term
    适用
    • 88
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    • 3
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    • 1
    宿主
    • 119
    • 2
    • 1
    • 1
    克隆类型
    • 112
    • 11
    多克隆
    标记
    • 42
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    This MAPK7 antibody is un-conjugated
    应用范围
    • 76
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to ERK5.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ERK5.
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAPK7 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
    别名
    MAPK7 / ERK5 (MAPK7 产品)
    别名
    BMK1 antibody, ERK4 antibody, ERK5 antibody, PRKM7 antibody, Erk5-T antibody, ATMPK7 antibody, F8D23.5 antibody, F8D23_5 antibody, MAP kinase 7 antibody, Bmk1 antibody, Erk5 antibody, Prkm7 antibody, ERK-5 antibody, bmk1 antibody, erk4 antibody, mapk7 antibody, prkm7 antibody, mitogen-activated protein kinase 7 antibody, MAP kinase 7 antibody, mitogen-activated protein kinase 7 L homeolog antibody, MAPK7 antibody, Mapk7 antibody, MPK7 antibody, mapk7.L antibody
    背景
    MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. The second proline-rich region may interact with actin targeting the kinase to a specific location in the cell. ERK5 is autophosphorylated on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent.Synonyms: Big MAP kinase 1, ERK4, Extracellular signal-regulated kinase 5, MAPK7, Mitogen-activated protein kinase 7
    基因ID
    5598, 9606
    UniProt
    Q13164
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
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