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BCKDK 抗体 (C-Term)

BCKDK 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN359194
发货至: 中国
  • 抗原 See all BCKDK 抗体
    BCKDK (Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK))
    抗原表位
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 54
    • 31
    • 17
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 52
    • 4
    克隆类型
    • 53
    • 3
    多克隆
    标记
    • 29
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCKDK antibody is un-conjugated
    应用范围
    • 49
    • 31
    • 10
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to BCKDK.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BCKDK.
    亚型
    Ig Fraction
    Top Product
    Discover our top product BCKDK Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    BCKDK (Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK))
    别名
    BCKDK (BCKDK 产品)
    别名
    cb233 antibody, zgc:55984 antibody, wu:fa04g07 antibody, wu:fb80b08 antibody, MGC78818 antibody, BCKDK antibody, AI327402 antibody, BCKDKD antibody, BDK antibody, branched chain ketoacid dehydrogenase kinase antibody, branched chain ketoacid dehydrogenase kinase S homeolog antibody, bckdk antibody, bckdk.S antibody, BCKDK antibody, Bckdk antibody
    背景
    The second major step in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine, is irreversibly catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD), an inner-mitochondrial enzyme complex composed of 3 catalytic components: a branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). The complex also contains 2 enzymes that regulated the state of activity of the BCKD complex: a kinase (BCKDK), and a phosphorylase. The ubiquitiously expressed kinase contains 1 histidine kinase domain. Maple syrup urine disease (MSUD) is a pathology secondary to an enzyme defect in the catabolic pathway of leucine, isoleucine, and valine. Accumulation of these amino acids and their corresponding keto acids results in encephalopathy and progressive neurodegeneration in infants not treated for MSUD.Synonyms: BCKD-kinase, BCKDHKIN, Branched-chain alpha-ketoacid dehydrogenase kinase, [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase mitochondrial
    基因ID
    10295, 9606
    UniProt
    O14874
    途径
    SARS-CoV-2 Protein Interactome
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