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SNCAIP 抗体 (C-Term)

SNCAIP 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN359008
发货至: 中国
  • 抗原 See all SNCAIP 抗体
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    抗原表位
    • 15
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 26
    • 24
    • 17
    人, 小鼠
    宿主
    • 38
    • 2
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SNCAIP antibody is un-conjugated
    应用范围
    • 28
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to Synphilin-1 (SNCAIP).
    纯化方法
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide in the C-terminal region of human Synphilin-1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SNCAIP Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    别名
    Synphilin 1 / SNCAIP (SNCAIP 产品)
    别名
    sncaip antibody, MGC88953 antibody, SNCAIP antibody, LOC100221074 antibody, SYPH1 antibody, Sph1 antibody, Syph1 antibody, 2810407O15Rik antibody, 4933427B05Rik antibody, BB104594 antibody, synuclein alpha interacting protein antibody, synuclein, alpha interacting protein antibody, synuclein, alpha interacting protein (synphilin) antibody, SNCAIP antibody, sncaip antibody, Sncaip antibody
    背景
    Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shows extensive homology with its human counterpart, especially in regions containing ankyrin-like motifs and the coiled-coil domain. Expression of mouse synphilin-1 in tissues is similar to its human counterpart. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and that Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. Role of synphilin-1 in synaptic function and protein degradation and in the molecular mechanisms leading to neurodegeneration in Parkinson diseaseSynonyms: Alpha-synuclein-interacting protein, Sph1, Synphilin-1
    基因ID
    9627
    NCBI登录号
    NP_005451
    UniProt
    Q9Y6H5
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