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BRAF 抗体 (pThr400)

BRAF 适用: 人 EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358444
发货至: 中国
  • 抗原 See all BRAF 抗体
    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
    抗原表位
    • 18
    • 13
    • 9
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    • 1
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    • 1
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    pThr400
    适用
    • 199
    • 72
    • 51
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 181
    • 18
    • 2
    克隆类型
    • 166
    • 35
    多克隆
    标记
    • 120
    • 13
    • 13
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    • 8
    • 4
    • 4
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    • 4
    • 4
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    • 1
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    This BRAF antibody is un-conjugated
    应用范围
    • 114
    • 113
    • 69
    • 32
    • 30
    • 18
    • 13
    • 13
    • 9
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    • 7
    • 5
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    Enzyme Immunoassay (EIA)
    特异性
    This antibody detects B-Raf proto-oncogene (BRAF) pThr400. Predicted to cross react with Mouse (100 % Antigen Homology).
    纯化方法
    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T400 of human BRAF.
    亚型
    Ig Fraction
    Top Product
    Discover our top product BRAF Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
    Abstract
    BRAF 产品
    背景
    BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.Synonyms: B-Raf proto-oncogene serine/threonine-protein kinase, BRAF, BRAF1, RAFB1, p94, v-Raf murine sarcoma viral oncogene homolog B1
    分子量
    84437 Da
    基因ID
    673, 9606
    UniProt
    P15056
    途径
    MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
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