Collagen Type IX 抗体 (Chain alpha 1)
适用: 人
EIA, IHC (p), WB
宿主: 兔
Polyclonal
unconjugated
2 images
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- 抗原 See all Collagen Type IX products
- Collagen Type IX
- 抗原表位
- Chain alpha 1
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- 特异性
- This antibody detects COL9A1 (Center). Predicted to cross react with Mouse (100 % Antigen Homology).
- 纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human COL9A1.
- 亚型
- Ig Fraction
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- 应用备注
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ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- Collagen Type IX
- Abstract
- Collagen Type IX 产品
- 背景
- COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20 % ) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule,and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.Synonyms: COL9A1
- 分子量
- 91855 Da
- 基因ID
- 1297, 9606
- UniProt
- P20849
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