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S100A1 抗体

S100A1 适用: 人, 小鼠, 大鼠, Cow, 猴 IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356473
发货至: 中国
  • 抗原 See all S100A1 抗体
    S100A1 (S100 Calcium Binding Protein A1 (S100A1))
    适用
    • 86
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    人, 小鼠, 大鼠, Cow, 猴
    宿主
    • 70
    • 24
    • 3
    克隆类型
    • 63
    • 35
    多克隆
    标记
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    This S100A1 antibody is un-conjugated
    应用范围
    • 61
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    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody stains schwannoma, ependymomas, astrogliomas, almost all benign and malignant melanoma and their metasis. Cellular localization: Cytoplasmic.
    交叉反应 (详细)
    Species reactivity (expected):Monkey, Rat and Mouse.
    Species reactivity (tested):Human, Bovine.
    纯化方法
    Protein A Chromatography
    免疫原
    Purified S100 protein from Bovine.
    亚型
    IgG
    Top Product
    Discover our top product S100A1 Primary Antibody
  • 应用备注
    Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 usingstreptavidinapprox. biotin system or polymer system. Immunofluorescence. Positive control: Melanoma or schwannoma.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    10 mM PO4, 150 mM NaCl, pH 7.4 containing 1 % BSA and 0.05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    This antibody should not be diluted in Buffer which contains Detergent.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    S100A1 (S100 Calcium Binding Protein A1 (S100A1))
    别名
    S100A1 (S100A1 产品)
    别名
    S100 antibody, S100-alpha antibody, S100A antibody, S100A1 antibody, DKFZp468K0511 antibody, AI266795 antibody, S100a antibody, S100 calcium binding protein A1 antibody, S100A1 antibody, S100a1 antibody, s100a1 antibody
    背景
    S100 protein is a type of low molecular weight protein found in vertebrates characterized by two calcium binding sites of the helix-loop-helix ("EF-hand type") conformation. There are at least 21 different types of S100 proteins. The name is derived from the fact that the protein is 100 % Soluble in ammonium sulfate at neutral pH . Most S100 proteins are homodimeric, consisting of two identical polypeptides held together by non-covalent bonds. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. Although S100 proteins are structurally similar to calmodulin, they differ in that they are cell-specific, expressed in particular cells at different levels depending on environmental factors. To contrast, calmodulin is a ubiquitous and universal intracellular Ca++ receptor widely expressed in many cells.S-100 is normally present in cells derived from the neural crest (Schwann cells, melanocytes, and glia cells), chondrocyte, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. It may be present in some breast epithelial cells.Synonyms: Astrocyte Marker, S-100 protein, S-100 protein alpha chain, S-100 protein alpha subunit, S-100 protein beta chain, S-100 protein beta subunit, S100 Alpha, S100 Beta, S100 Calcium binding protein, S100A, S100B
    基因ID
    6271
    NCBI登录号
    NP_006262
    UniProt
    P23297
    途径
    Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
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