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MDS1 and EVI1 Complex Locus (MECOM) (N-Term) 抗体

ABIN356376 产品详细信息, 供应商: Log in to see
抗原
  • evi1
  • im:7140716
  • prdm3
  • EVI1
  • AML1-EVI-1
  • MDS1
  • MDS1-EVI1
  • PRDM3
  • D630039M04Rik
  • Evi-1
  • Evi1
  • Jbo
  • Mds
  • Mds1
  • Mds1-Evi1
  • Prdm3
  • Znfpr1b1
  • AML1
  • AMLCR1
  • CBFA2
  • EVI-1
  • PEBP2aB
  • MDS1 and EVI1 complex locus
  • runt-related transcription factor 1
  • mecom
  • MECOM
  • LOC100343228
  • Mecom
  • RUNX1
抗原表位
N-Term
28
17
17
15
9
5
5
4
4
3
3
2
2
2
1
1
1
1
1
适用
人, 小鼠
105
33
9
4
4
3
3
2
1
1
1
宿主
小鼠
72
30
15
克隆类型 (克隆位点)
单克隆 ()
标记
非结合性
6
6
6
6
6
6
应用范围
Enzyme Immunoassay (EIA), Western Blotting (WB)
104
65
11
5
3
2
1
1
1
1
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免疫原 This antibody was raised using purified recombinant GST fusion protein encoding theN-terminal part of human PRDM3.
克隆位点 47AT612-84-88
亚型 IgG1
特异性 This antibody is specific to PRDM3.
产品特性 Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1
纯化方法 Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
别名 MDS1 (MECOM Antibody 摘要)
背景 Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. MDS1, first identified as part of a fusion transcript resulting from the t(3,21)(q26,q22), encodes a small protein of unknown function. EVI1 encodes a zinc finger protein inappropriately overexpressed by chromosomal rearrangements. EVI1 and MDS1 are unusual in that they can either encode separate proteins, or they can be expressed as a fusion protein MDS1/EVI1. EVI1 and MDS1/EVI1 have opposite functions as transcription factors.Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1
基因ID 2122
UniProt Q13465
应用备注 ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
状态 Liquid
浓度 0.25 mg/mL
缓冲液 PBS containing 0.09 % (W/V) Sodium Azide as preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
有效期 12 months
厂商提供的图像
Western Blotting (WB) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (N-Term) 抗体 (ABIN356376) anti-MDS1 and EVI1 Complex Locus (MECOM) (N-Term) antibody