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- 抗原 See all MECOM 抗体
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MECOM antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is specific to PRDM3.
- 产品特性
- Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1
- 纯化方法
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- This antibody was raised using purified recombinant GST fusion protein encoding theN-terminal part of human PRDM3.
- 克隆位点
- 47AT612-84-88
- 亚型
- IgG1
- Top Product
- Discover our top product MECOM Primary Antibody
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anti-MDS1 and EVI1 Complex Locus (MECOM) antibody
MECOM 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) (AA 964-1013) antibodyMECOM 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) (C-Term) antibodyMECOM 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) (C-Term) antibodyMECOM 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) (AA 80-169) antibodyMECOM 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) (AA 952-1050) antibodyMECOM 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6A9 unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) (N-Term) antibodyMECOM 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) (AA 534-632) antibodyMECOM 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) antibodyMECOM 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MDS1 and EVI1 Complex Locus (MECOM) antibodyMECOM 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
- 别名
- MDS1 (MECOM 产品)
- 别名
- AML1-EVI-1 antibody, EVI1 antibody, MDS1 antibody, MDS1-EVI1 antibody, PRDM3 antibody, D630039M04Rik antibody, Evi-1 antibody, Evi1 antibody, Jbo antibody, Mds antibody, Mds1 antibody, Mds1-Evi1 antibody, Prdm3 antibody, Znfpr1b1 antibody, evi1 antibody, im:7140716 antibody, prdm3 antibody, evi-1 antibody, mecom antibody, mecom-a antibody, mecom-b antibody, xEvi-1 antibody, evi1-B antibody, MDS1 and EVI1 complex locus antibody, MDS1 and EVI1 complex locus L homeolog antibody, MDS1 and EVI1 complex locus S homeolog antibody, MECOM antibody, Mecom antibody, mecom antibody, mecom.L antibody, mecom.S antibody
- 背景
- Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. MDS1, first identified as part of a fusion transcript resulting from the t(3,21)(q26,q22), encodes a small protein of unknown function. EVI1 encodes a zinc finger protein inappropriately overexpressed by chromosomal rearrangements. EVI1 and MDS1 are unusual in that they can either encode separate proteins, or they can be expressed as a fusion protein MDS1/EVI1. EVI1 and MDS1/EVI1 have opposite functions as transcription factors.Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1
- 基因ID
- 2122
- UniProt
- Q13465
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