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TRPV1 抗体 (1st Cytoplasmic Loop)

TRPV1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN351255
发货至: 中国
  • 抗原 See all TRPV1 抗体
    TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))
    抗原表位
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    1st Cytoplasmic Loop
    适用
    • 37
    • 28
    • 24
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 52
    • 6
    • 2
    • 2
    克隆类型
    • 57
    • 5
    多克隆
    标记
    • 39
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This TRPV1 antibody is un-conjugated
    应用范围
    • 31
    • 23
    • 13
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for TRPV1.
    免疫原
    A synthetic peptide from 1t cytoplasmic loop of human TRPV1 (VR1, capsaicin receptor, vanilloid receptor 1) conjugated to an immunogenic carrier protein was used as the antigen.
    亚型
    IgG
    Top Product
    Discover our top product TRPV1 Primary Antibody
  • 应用备注
    A concentration of 10-50 µg/ml is recommended.
    The optimal concentration should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))
    别名
    TRPV1 (TRPV1 产品)
    别名
    si:dkey-9e15.2 antibody, VR.5'sv antibody, Vr1 antibody, Vr1l1 antibody, VR1 antibody, OTRPC1 antibody, TRPV1alpha antibody, TRPV1beta antibody, VR-1 antibody, transient receptor potential cation channel, subfamily V, member 1 antibody, transient receptor potential cation channel subfamily V member 1 antibody, trpv1 antibody, Trpv1 antibody, TRPV1 antibody
    背景
    Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.
    Function: Receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. May be involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Responses evoked by low pH and heat, and capsaicin can be antagonized by capsazepine. Also known as: TrpV1, osm-9-like TRP channel 1, OTRPC1, vanilloid receptor 1, capsaicin receptor, VR1, transient receptor potential cation channel subfamily V member 1.
    途径
    Dicarboxylic Acid Transport
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