(1 reference)-
- 抗原 See all TRPM8 抗体
- TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRPM8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Specific for TRPM8.
- 交叉反应
- 人
- 交叉反应 （详细）
- Other species not yet tested.
- 纯化方法
- IgG
- 免疫原
- A synthetic peptide from human TRPM8 conjugated to blue carrier protein was used as the antigen.
- 亚型
- IgG
- Top Product
- Discover our top product TRPM8 Primary Antibody
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anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 926-956), (C-Term) antibody
TRPM8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14420 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 521-552) antibodyTRPM8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 263-292) antibodyTRPM8 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (3rd Extracellular Loop), (AA 917-929) antibodyTRPM8 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, Neut, IP, LCI 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 1-192) antibodyTRPM8 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (N-Term) antibodyTRPM8 适用: 人, 豚鼠, 兔, 犬, Bat, 猴, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 933-963) antibodyTRPM8 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 980-1104) antibodyTRPM8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (Internal Region) antibodyTRPM8 适用: 人, 大鼠, 小鼠, 豚鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 251-300) antibodyTRPM8 适用: 人, 豚鼠, 兔, 犬, 马, Pig, Cow, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- 注意事项
- Avoid freeze and thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- 有效期
- 12 months
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: "TRPM8 thermosensation in poikilotherms mediates both skin colour and locomotor performance responses to cold temperature." in: Communications biology, Vol. 6, Issue 1, pp. 127, (2023) (PubMed).
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: "TRPM8 thermosensation in poikilotherms mediates both skin colour and locomotor performance responses to cold temperature." in: Communications biology, Vol. 6, Issue 1, pp. 127, (2023) (PubMed).
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- 抗原
- TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))
- 别名
- TRPM8 (TRPM8 产品)
- 别名
- TRPM8 antibody, trpp8 antibody, ltrpc6 antibody, trpm8b antibody, LTRPC6 antibody, TRPP8 antibody, CMR1 antibody, LTrpC-6 antibody, Trp-p8 antibody, transient receptor potential cation channel subfamily M member 8 antibody, transient receptor potential cation channel subfamily M member 8b L homeolog antibody, transient receptor potential cation channel, subfamily M, member 8 antibody, TRPM8 antibody, trpm8b.L antibody, Trpm8 antibody
- 背景
- FUNCTION: Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH . Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in prostate. Also expressed in most in prostate tumors. Also expressed in non-prostatic primary tumors such as colon, lung, breast and skin tumors. MISCELLANEOUS: The sensation of coolness triggered by eucalyptol or menthol may be explained by the fact that menthol and cool temperatures sensations are detected by this protein. MISCELLANEOUS: Its expression in most prostate tumors as well as the presence of an immunogenic epitope suggest that it may be suitable for the design of peptide vaccination strategies for prostate cancers.,Mammalian TRPM,Transient receptor potential cation channel subfamily M member 8, transient receptor potential-p8, Trp-p8, long transient receptor potential channel 6, LTrpC6, TRPP8, LTRPC6, MGC2849
- UniProt
- Q7Z2W7
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