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SUMO4 抗体 (N-Term)

SUMO4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350888
发货至: 中国
  • 抗原 See all SUMO4 抗体
    SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    N-Term
    适用
    • 54
    • 18
    • 18
    宿主
    • 51
    • 3
    克隆类型
    • 43
    • 11
    多克隆
    标记
    • 25
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SUMO4 antibody is un-conjugated
    应用范围
    • 38
    • 27
    • 25
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for SUMO4.
    免疫原
    A synthetic peptide from the n-terminal of human SUMO4 (Small ubiquitin-related modifier4) conjugated to an immunogenic carrier protein was used as the antigen.
    亚型
    IgG
    Top Product
    Discover our top product SUMO4 Primary Antibody
  • 应用备注
    A concentration of 10-50 µg/ml is recommended.
    The optimal concentration should be determined by the end user.
    Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))
    别名
    SUMO 4 (SUMO4 产品)
    别名
    IDDM5 antibody, SMT3H4 antibody, SUMO-4 antibody, dJ281H8.4 antibody, small ubiquitin-like modifier 4 antibody, small ubiquitin-related modifier 4 antibody, SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae) antibody, SUMO4 antibody, sumo4 antibody
    背景
    Function: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.
    Tissue specificity: Expressed mainly in adult and embryonic kidney. Expressed at various levels in immune tissues, with the highest expression in the lymph node and spleen. Post-translational modification: In contrast to SUMO1, SUMO2 and SUMO3, seems to be insensitive to sentrin-specific proteases due to the presence of Pro-90. This may impair processing to mature form and conjugation to substrates. Also known as: Small ubiquitin-related modifier 4, SUMO-4, Small ubiquitin-like protein 4, SUMO4, SMT3H4.
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