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STIM1 抗体 (Extracellular Domain)

STIM1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350881
发货至: 中国
  • 抗原 See all STIM1 抗体
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    抗原表位
    • 16
    • 15
    • 15
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-100, Extracellular Domain
    适用
    • 74
    • 56
    • 26
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 78
    • 9
    • 1
    • 1
    克隆类型
    • 71
    • 18
    多克隆
    标记
    • 41
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This STIM1 antibody is un-conjugated
    应用范围
    • 45
    • 31
    • 26
    • 26
    • 25
    • 20
    • 12
    • 11
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for STIM1.
    免疫原
    A synthetic peptide from aa region 50-100 of extracellular domain of human STIM1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
    亚型
    IgG
    Top Product
    Discover our top product STIM1 Primary Antibody
  • 应用备注
    A concentration of 10-50 µg/ml is recommended.
    The optimal concentration should be determined by the end user. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    别名
    STIM1 (STIM1 产品)
    别名
    stim1 antibody, MGC76045 antibody, STIM1 antibody, si:dkey-24p1.5 antibody, MGC154748 antibody, si:ch211-112l17.2 antibody, Stim1 antibody, D11S4896E antibody, GOK antibody, TAM antibody, SIM antibody, stromal interaction molecule 1 antibody, stromal interaction molecule 1a antibody, stromal interaction molecule 1 L homeolog antibody, stromal interaction molecule 1b antibody, STIM1 antibody, stim1 antibody, stim1a antibody, stim1.L antibody, stim1b antibody, Stim1 antibody
    背景
    Function: Plays a role in mediating Ca2+ influx following depletion of intracellular Ca2+ stores. Acts as Ca2+ sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca2+ depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit, TMEM142A/ORAI1.
    Subcellular location: Cell membrane, Single-pass type I membrane protein. Endoplasmic reticulum membrane, Single-pass type I membrane protein. Note: Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium.
    Tissue specificity: Ubiquitously expressed in various human primary cells and tumor cell lines. Also known as: STIM1, GOK.
    途径
    TCR Signaling, BCR Signaling
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