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NGFR 抗体 (Extracellular Domain)

NGFR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350712
发货至: 中国
  • 抗原 See all NGFR 抗体
    NGFR (Nerve Growth Factor Receptor (NGFR))
    抗原表位
    • 16
    • 13
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 161
    • 61
    • 55
    • 29
    • 27
    • 26
    • 26
    • 21
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 92
    • 76
    • 4
    • 1
    克隆类型
    • 94
    • 79
    多克隆
    标记
    • 91
    • 15
    • 12
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NGFR antibody is un-conjugated
    应用范围
    • 106
    • 82
    • 61
    • 56
    • 48
    • 30
    • 27
    • 20
    • 20
    • 14
    • 14
    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for p75NTR.
    交叉反应
    人, 小鼠, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from the extracellular domain of human p75NTR (low affinity NGF receptor, p75, LNGFR, p75NTR) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in many other species including mouse and rat.
    亚型
    IgG
    Top Product
    Discover our top product NGFR Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    NGFR (Nerve Growth Factor Receptor (NGFR))
    别名
    p75NTR (NGFR 产品)
    别名
    ngfr antibody, wu:fb38c02 antibody, wu:fc10h01 antibody, CD271 antibody, Gp80-LNGFR antibody, TNFRSF16 antibody, p75(NTR) antibody, p75NTR antibody, LNGFR antibody, RNNGFRR antibody, Tnfrsf16 antibody, p75 antibody, NRH1b antibody, fullback antibody, nrh1 antibody, p75ntr antibody, tnfrsf16 antibody, p75NGFR antibody, nerve growth factor receptor antibody, neurotrophin receptor associated death domain antibody, nerve growth factor receptor S homeolog antibody, nerve growth factor receptor (TNFR superfamily, member 16) antibody, NGFR antibody, nradd antibody, Ngfr antibody, ngfr.S antibody
    背景
    FUNCTION: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/<||a href="http://www.osenses.com/bex-family-c-21_106.html">BEX3<||/a>. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with <||a href="http://www.osenses.com/advanced_search_result.php?antigen=sqstm1&x=0&y=0">SQSTM1<||/a> which bridges NGFR to NTRK1. Interacts with <||a href="http://www.osenses.com/bex-family-c-21_106.html">BEX1<||/a>. Interacts with ARMS and NTRK1. Can form a ternary complex with NTRK1 and ARMS and this complex is affected by the expression levels of ARMS. An increase in ARMS expression leads to a decreased association of NGFR and NTRK1. Interacts with LINGO1. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.,Neurotrophic Receptors,Low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR, p75, LNGFR, p75NTR, RNNGFRR
    UniProt
    P08138
    途径
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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