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GPR143 抗体 (4th Cytoplasmic Domain)

GPR143 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350534
发货至: 中国
  • 抗原 See all GPR143 抗体
    GPR143 (G Protein-Coupled Receptor 143 (GPR143))
    抗原表位
    • 15
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    4th Cytoplasmic Domain
    适用
    • 38
    • 11
    • 10
    • 1
    宿主
    • 36
    • 2
    克隆类型
    • 38
    多克隆
    标记
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPR143 antibody is un-conjugated
    应用范围
    • 22
    • 13
    • 13
    • 11
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for OA1.
    交叉反应
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from the 4th cytoplasmic domain of human OA1 conjugated to blue carrier protein was used as the antigen.
    亚型
    IgG
    Top Product
    Discover our top product GPR143 Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    GPR143 (G Protein-Coupled Receptor 143 (GPR143))
    别名
    OA1 (GPR143 产品)
    背景
    Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. FUNCTION: Not known, binds heterotrimeric G proteins. SUBCELLULAR LOCATION: Melanosome membrane, Multi-pass membrane protein. Note: Targeted to intracellular organelles, namely the melanosomes in pigment cells. TISSUE SPECIFICITY: Exclusively expressed in pigment cells. DISEASE: Defects in GPR143 are the cause of ocular albinism type 1 (OA1), also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.,Vision,G-protein coupled receptor 143, ocular albinism type 1 protein, GPR143, OA1
    UniProt
    P51810
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