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LC3C 抗体

MAP1LC3C 适用: 人 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN350463
发货至: 中国
  • 抗原 See all LC3C (MAP1LC3C) 抗体
    LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
    适用
    • 44
    • 3
    • 2
    宿主
    • 43
    • 1
    绵羊
    克隆类型
    • 44
    多克隆
    标记
    • 19
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LC3C antibody is un-conjugated
    应用范围
    • 33
    • 27
    • 9
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for MAP1LC3C.
    交叉反应
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from human microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C, MAP1A/MAP1B LC3 C) conjugated to an immunogenic carrier protein has been used as the immunogen.
    亚型
    IgG
    Top Product
    Discover our top product MAP1LC3C Primary Antibody
  • 应用备注
    IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
    别名
    MAP1LC3C (MAP1LC3C 产品)
    别名
    MAP1LC3C antibody, MGC154878 antibody, ATG8J antibody, LC3C antibody, microtubule associated protein 1 light chain 3 gamma antibody, microtubule associated protein 1 light chain 3 gamma L homeolog antibody, MAP1LC3C antibody, map1lc3c antibody, map1lc3c.L antibody
    背景
    Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes). SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane, Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane, Lipid-anchor. Note: LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in placenta, lung and ovary. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.,Mammalian Autophagy,Microtubule-associated proteins 1A/1B light chain 3C, MAP1LC3C, MAP1A/MAP1B LC3 C, MAP1A/1B light chain 3 C, MAP1 light chain 3-like protein 3, Autophagy-related protein LC3 C, Autophagy-related ubiquitin-like modifier LC3C
    UniProt
    Q9BXW4
    途径
    Autophagy
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