KCNJ2 抗体 (Cytoplasmic Domain)
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- 抗原 See all KCNJ2 抗体
- KCNJ2 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2))
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抗原表位
- Cytoplasmic Domain
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNJ2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Specific for KCNJ2.
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 （详细）
- Other species not yet tested.
- 纯化方法
- IgG
- 免疫原
- A synthetic peptide from the cytoplasmic domain of mouse KCNJ2 (HIRK1, IRK1, Kir2.1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and human.
- 亚型
- IgG
- Top Product
- Discover our top product KCNJ2 Primary Antibody
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody
KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (HRP)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 HRP
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (FITC)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 FITC
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (Biotin)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 Biotin
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (PE)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 PE
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (APC)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 APC
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (PerCP)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 PerCP
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (Atto 488)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 Atto 488
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (Atto 594)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 Atto 594
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) (AA 41-64) antibody (Atto 390)KCNJ2 适用: 小鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal S112 Atto 390
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- 应用备注
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- 注意事项
- Avoid freeze and thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- 有效期
- 12 months
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- 抗原
- KCNJ2 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2))
- 别名
- KCNJ2 (KCNJ2 产品)
- 别名
- KCNJ2 antibody, ATFB9 antibody, HHBIRK1 antibody, HHIRK1 antibody, IRK1 antibody, KIR2.1 antibody, LQT7 antibody, SQT3 antibody, Kir2.1 antibody, Kcnf1 antibody, IRK-1 antibody, potassium voltage-gated channel subfamily J member 2 antibody, potassium inwardly-rectifying channel, subfamily J, member 2 antibody, KCNJ2 antibody, Kcnj2 antibody
- 背景
- FUNCTION: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium. Tissue specificity: Heart, brain, placenta, lung, skeletal muscle, and kidney. Diffusely distributed throughout the brain. Subcellular location: Membrane, Multi-pass membrane protein. Involvement in disease: Defects in KCNJ2 are the cause of long QT syndrome type 7 (LQT7), also called Andersen syndrome or Andersen cardiodysrhythmic periodic paralysis. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. LQT7 manifests itself as a clinical triad consisting of potassium-sensitive periodic paralysis, ventricular ectopy and dysmorphic features. Defects in KCNJ2 are the cause of short QT syndrome type 3 (SQT3). Short QT syndromes are heart disorders characterized by idiopathic persistently and uniformly short QT interval on ECG in the absence of structural heart disease in affected individuals. They cause syncope and sudden death. SQT3 has a unique ECG phenotype characterized by asymmetrical T waves.,Inward Rectifier,Inward rectifier potassium channel 2, Potassium channel, inwardly rectifying subfamily J member 2, Inward rectifier K(+) channel Kir2.1, Cardiac inward rectifier potassium channel, IRK1
- UniProt
- P35561
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