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CACNB4 抗体 (C-Term)

CACNB4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350161
发货至: 中国
  • 抗原 See all CACNB4 抗体
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    抗原表位
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 25
    • 16
    • 14
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 22
    • 4
    • 1
    克隆类型
    • 25
    • 2
    多克隆
    标记
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNB4 antibody is un-conjugated
    应用范围
    • 15
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for CACNB4.
    交叉反应
    人, 小鼠, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from the c-terminal region of human CACNB4 (CACB4, Voltage dependent L-type calcium channel subunit beta-4) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in many species including mouse and rat.
    亚型
    IgG
    Top Product
    Discover our top product CACNB4 Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    别名
    CACNB4 (CACNB4 产品)
    别名
    CAB4 antibody, CACNLB4 antibody, EA5 antibody, EIG9 antibody, EJM antibody, EJM4 antibody, EJM6 antibody, 3110038O15Rik antibody, Cchb4 antibody, lethargic antibody, lh antibody, CACNB4 antibody, cacnb4.2 antibody, calcium voltage-gated channel auxiliary subunit beta 4 antibody, calcium channel, voltage-dependent, beta 4 subunit antibody, calcium channel, voltage-dependent, beta 4a subunit antibody, CACNB4 antibody, Cacnb4 antibody, cacnb4.1 antibody, cacnb4 antibody, cacnb4a antibody
    背景
    FUNCTION: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB4 are associated with susceptibility to idiopathic generalized epilepsy (IGE). IGE is characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain. Defects in CACNB4 are a cause of juvenile myoclonic epilepsy (EJM). EJM is a subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue. Tissue specificity: Expressed predominantly in the cerebellum and kidney.,Beta Subunit,CACB4, Voltage-dependent L-type calcium channel subunit beta-4, Calcium channel voltage-dependent subunit beta 4
    UniProt
    O00305
    途径
    cAMP Metabolic Process, Skeletal Muscle Fiber Development
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