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CACNB2 抗体 (C-Term)

CACNB2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350158
发货至: 中国
  • 抗原 See all CACNB2 抗体
    CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))
    抗原表位
    • 12
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 64
    • 44
    • 33
    • 14
    • 13
    • 12
    • 12
    • 9
    • 9
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    宿主
    • 59
    • 19
    • 1
    克隆类型
    • 61
    • 18
    多克隆
    标记
    • 44
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNB2 antibody is un-conjugated
    应用范围
    • 65
    • 33
    • 20
    • 16
    • 14
    • 13
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for CACNB2.
    交叉反应
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from the c-terminal region of human CACNB2 (CAB2, MYSB) conjugated to an immunogenic carrier protein was used as the antigen.
    亚型
    IgG
    Top Product
    Discover our top product CACNB2 Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))
    别名
    CACNB2 (CACNB2 产品)
    别名
    CACNLB2 antibody, CAVB2 antibody, MYSB antibody, AW060387 antibody, CAB2 antibody, Cavbeta2 antibody, Cchb2 antibody, Cacnlb2 antibody, Cacnb2 antibody, CACNB2 antibody, CACNB2.2 antibody, cacnb2a antibody, im:7141271 antibody, si:dkey-32m20.2 antibody, calcium voltage-gated channel auxiliary subunit beta 2 antibody, calcium channel, voltage-dependent, beta 2 subunit antibody, calcium channel, voltage-dependent, beta 2b antibody, CACNB2 antibody, Cacnb2 antibody, cacnb2b antibody
    背景
    Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4). BRS4 is a heart disease characterized by the association of Brugada syndrome with shortened QT intervals. Brugada syndrome is a tachyarrhythmia characterized by right bundle branch block and ST segment elevation on an electrocardiogram (ECG). It can cause the ventricles to beat so fast that the blood is prevented from circulating efficiently in the body. When this situation occurs (called ventricular fibrillation), the individual will faint and may die in a few minutes if the heart is not reset. Subcellular location: Cell membrane âÄ° sarcolemma, Peripheral membrane protein, Cytoplasmic side Tissue specificity: Expressed in all tissues.,Beta Subunit,Voltage-dependent L-type calcium channel subunit beta-2, CAB2, Calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, CACNLB2
    UniProt
    Q08289
    途径
    Skeletal Muscle Fiber Development
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